CAS 789-47-9

2-Chrysenamine

Description:

2-Chrysenamine, with the CAS number 789-47-9, is an organic compound that belongs to the class of amines. It is derived from chrysene, a polycyclic aromatic hydrocarbon, by the introduction of an amino group at the second position of the chrysene structure. This compound typically appears as a solid and is characterized by its aromatic properties, which contribute to its stability and potential reactivity. 2-Chrysenamine may exhibit various chemical behaviors, including the ability to participate in electrophilic aromatic substitution reactions due to the presence of the amino group, which can act as a nucleophile. Additionally, it may have implications in biological systems, particularly in studies related to mutagenicity and carcinogenicity, as many amines derived from polycyclic aromatic hydrocarbons are known to have such properties. Safety data should be consulted for handling and exposure risks, as with many organic compounds, particularly those related to aromatic amines.

Formula: C₁₈H₁₃N

InChI: InChI=1S/C18H13N/c19-14-7-10-16-13(11-14)6-9-17-15-4-2-1-3-12(15)5-8-18(16)17/h1-11H,19H2

InChI key: InChIKey=KSDIHKMNSYWRFB-UHFFFAOYSA-N

SMILES: NC=1C=C2C(C3=C(C=4C(C=C3)=CC=CC4)C=C2)=CC1

Synonyms:

• 2-Aminochrysene
• Ai3-52508
• Brn 2806929
• Ccris 6985
• Nsc 14764
• 2-Chrysenamine
• Chrysen-2-Amine
• Chrysene-2-amine
• chrysen-2-ylamine

2-Aminochrysene

CAS: 789-47-9

2-Aminochrysene is a chemical that binds to DNA and causes a genotoxic effect. It has been shown to be carcinogenic to rats and is carcinogenic in humans. 2-Aminochrysene is metabolized by conjugation with glucuronic acid or glutathione, which are found in the liver, kidney, and other tissues. The binding constants for 2-aminochrysene were measured using the calf thymus DNA as a substrate and amines as ligands. Transfer of 2-aminochrysene from the plasma membrane to the cytosol was observed in cells treated with nitrous oxide (NO). The cytosolic enzyme binding assay showed that 2-aminochrysene binds to the S9 protein of hepatic microsomes.
2-Aminochrysene has also been shown to inhibit phospholipase A2 activity, which may be due to its ability to bind to the enzyme's active site.

Formula: C₁₈H₁₃N

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 243.3 g/mol

Ref: 3D-FA66865