CAS 78919-26-3

Isoursodeoxycholic acid

Description:

Isoursodeoxycholic acid, with the CAS number 78919-26-3, is a bile acid derivative that plays a role in the digestion and absorption of fats and fat-soluble vitamins in the intestine. It is a stereoisomer of deoxycholic acid, which is produced from the bacterial metabolism of primary bile acids in the colon. This compound is characterized by its hydrophobic and amphipathic properties, allowing it to interact with lipid membranes and facilitate emulsification of dietary fats. Isoursodeoxycholic acid has been studied for its potential therapeutic applications, particularly in the context of liver diseases and metabolic disorders, due to its influence on cholesterol metabolism and its ability to modulate gut microbiota. Additionally, it may exhibit anti-inflammatory properties, making it a subject of interest in research related to gastrointestinal health. Its solubility and stability in various pH environments are also important characteristics that influence its biological activity and potential applications in pharmaceuticals.

Formula: C₂₄H₄₀O₄

InChI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16+,17-,18+,19+,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=RUDATBOHQWOJDD-DNMBCGTGSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyms:

• (3β,5β,7β)-3,7-Dihydroxycholan-24-oic acid
• 3b,7b-Dihydroxy-5b-cholan-24-oic acid
• 3β,7β-Dihydroxy-5β-cholanic acid
• 3β,7β-Dihydroxy-5β-cholanoic acid
• 3β-Ursodeoxycholic acid
• Cholan-24-oic acid, 3,7-dihydroxy-, (3beta,5beta,7beta)-
• Cholan-24-oic acid, 3,7-dihydroxy-, (3β,5β,7β)-
• Isoursodeoxycholic acid
• IsoUDCA
• 3-epi-Ursodeoxycholic acid
• Ursodeoxycholic Acid EP Impurity H/3β-Ursodeoxycholic Acid/Isoursodeoxycholic Acid/(3β,5β,7β)-3,7-Dihydroxycholan-24-oic Acid
• (4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• Ursodeoxycholic Acid Impurity 8（Ursodeoxycholic Acid EP Impurity H）
• Ursodiol Impurity H
• Ursodeoxycholic Acid EP Impurity H

Ursodiol Related Compound H (3β, 7β-Dihydroxy-5β-cholan-24-oic acid)

CAS: 78919-26-3

Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoi

Formula: C₂₄H₄₀O₄

Color and Shape: White Fine Powder

Molecular weight: 392.29266

Ref: 45-1707792

Isoursodeoxycholic Acid

CAS: 78919-26-3

Formula: C₂₄H₄₀O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 392.5720

Ref: IN-DA00G53D

3β-Ursodeoxycholic acid

CAS: 78919-26-3

3β-Ursodeoxycholic acid

Purity: ≥98%

Molecular weight: 392.57g/mol

Ref: 54-BUP08849

Ursodiol USP Related Compound H (Ursodeoxycholic Acid EP Impurity H, Isoursodeoxycholic Acid)

CAS: 78919-26-3

Formula: C₂₄H₄₀O₄

Molecular weight: 392.58

Ref: 4Z-U-0218

3β-Ursodeoxycholic acid

CAS: 78919-26-3

Molecular weight: 392.58

Ref: 10-F986898

3β-Ursodeoxycholic Acid

Controlled Product

CAS: 78919-26-3

Impurity Ursodeoxycholic Acid EP Impurity H
Applications 3β-Ursodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity H) is used as an anticholelithogenic.
References Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986), Poupon, R.E, et al.: N. Engl. J. Med., 324, 1548 (1991)

Formula: C₂₄H₄₀O₄

Color and Shape: Neat

Molecular weight: 392.57

Ref: TR-U850005

Ursodeoxycholic Acid EP Impurity H

CAS: 78919-26-3

Formula: C₂₄H₄₀O₄

Molecular weight: 392.58

Ref: ST-EA-CP-U1008

3β-Ursodeoxycholic acid

Controlled Product

CAS: 78919-26-3

3beta-Ursodeoxycholic acid is a bile acid that is synthesized in the liver and secreted into the intestine. It is used as a treatment for congestive heart failure, HIV infection, bowel disease, and autoimmune diseases. 3beta-Ursodeoxycholic acid has been shown to be a potent inhibitor of hydroxylation of cholesterol in the liver. It also exhibits an ability to increase the transport rate of cholesterol from the liver to other tissues in the body. 3beta-Ursodeoxycholic acid inhibits monoethyl ether formation by competing with ethylene oxide for binding sites on microsomal proteins. This compound also protects against primary sclerosing cholangitis and ursodiol therapy by preventing enzymatic inactivation of bile acids.

Formula: C₂₄H₄₀O₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 392.57 g/mol

Ref: 3D-FU28646

3β-Ursodeoxycholic Acid-d4

Controlled Product

CAS: 78919-26-3

Formula: C₂₄H₃₆D₄O₄

Color and Shape: Neat

Molecular weight: 396.6

Ref: TR-U850006

3β-Ursodeoxycholic Acid-d5

Controlled Product

CAS: 78919-26-3

Formula: C₂₄D₅H₃₅O₄

Color and Shape: Neat

Molecular weight: 397.603

Ref: TR-U850004

3β-Ursodeoxycholic acid

CAS: 78919-26-3

3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid that exhibits good tolerance and good intestinal absorption.Cost-effective and quality-assured.

Formula: C₂₄H₄₀O₄

Purity: 98% - 99.89%

Color and Shape: Solid

Molecular weight: 392.57

Ref: TM-T13506