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CAS 79-60-7

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(9xi)-9-fluoro-17,21-dihydroxypregn-4-ene-3,11,20-trione

Description:
The chemical substance known as (9xi)-9-fluoro-17,21-dihydroxypregn-4-ene-3,11,20-trione, with the CAS number 79-60-7, is a synthetic corticosteroid. It is characterized by its fluorinated structure, which enhances its anti-inflammatory and immunosuppressive properties. This compound features a pregnane backbone, typical of steroid hormones, and contains multiple hydroxyl groups that contribute to its biological activity. The presence of the fluorine atom at the 9-position increases its potency and stability compared to non-fluorinated analogs. It is commonly used in medical applications to treat various inflammatory conditions and autoimmune disorders due to its ability to modulate immune responses. The compound's pharmacological effects are mediated through its interaction with glucocorticoid receptors, leading to alterations in gene expression. As with many corticosteroids, it may have side effects, including potential impacts on metabolism and immune function, necessitating careful management in therapeutic contexts. Overall, this substance exemplifies the modifications made to steroid structures to enhance therapeutic efficacy.
Formula:C21H27FO5
InChI:InChI=1/C21H27FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-15,23,27H,3-8,10-11H2,1-2H3/t14-,15-,18-,19-,20-,21?/m0/s1
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Found 1 products.
  • 9-Fluoro-17,21-Dihydroxy-Pregn-4-Ene-3,11,20-Trione
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    9-Fluoro-17,21-Dihydroxy-Pregn-4-Ene-3,11,20-Trione

    Controlled Product
    CAS:
    9-Fluoro-17,21-Dihydroxy-Pregn-4-Ene-3,11,20-Trione is a potent mineralocorticoid that is used to diagnose both congenital and acquired forms of adrenal insufficiency. This drug acts by increasing the synthesis of aldosterone and hydrocortisone in the adrenal glands. It is also used to treat Addison's disease and congenital adrenal hyperplasia. 9-Fluoro-17,21-Dihydroxy-Pregn-4-Ene-3,11,20-Trione has been shown to be an effective treatment for patients with myeloproliferative diseases who are resistant to vinblastine or colchicine. The drug binds to the proenzyme form of plasminogen activator (PA) and induces its conversion into active plasminogen activator (PA).
    Formula:C21H27FO5
    Purity:Min. 95%
    Molecular weight:378.43 g/mol

    Ref: 3D-FF92392

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