CAS 791-69-5

9,11-Dehydroestradiol

Description:

9,11-Dehydroestradiol is a synthetic derivative of estradiol, a key estrogen hormone involved in various physiological processes. This compound is characterized by the absence of hydrogen atoms at the 9 and 11 positions of the steroid nucleus, which alters its biological activity compared to its parent compound. It has a molecular formula that reflects its steroid structure, typically exhibiting a fused ring system common to steroid hormones. 9,11-Dehydroestradiol is known for its potential use in research related to hormonal therapies and its effects on estrogen receptors. Its unique structure may influence its binding affinity and efficacy in various biological systems. The compound is often studied in the context of its metabolic pathways and interactions with other hormones. As with many steroid derivatives, it is important to handle 9,11-Dehydroestradiol with care, considering its potential biological effects and the need for proper safety protocols in laboratory settings.

Formula: C₁₈H₂₂O₂

InChI: InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,8,10,15-17,19-20H,2,4,6-7,9H2,1H3/t15-,16+,17+,18+/m1/s1

InChI key: InChIKey=FABGTKBXHAEVKL-OWSLCNJRSA-N

SMILES: C[C@@]12[C@]([C@]3(C(C=4C(CC3)=CC(O)=CC4)=CC1)[H])(CC[C@@H]2O)[H]

Synonyms:

• Estra-1,3,5(10),9(11)-tetraene-3,17β-diol
• Δ9,11-Estradiol
• J 1213
• (17β)-Estra-1,3,5(10),9(11)-tetraene-3,17-diol
• Estra-1,3,5(10),9(11)-tetraene-3,17-diol, (17β)-
• 9-DEHYDROESTRADIOL
• 1,3,5(10), 9(11)-ESTRATETRAEN-3,17-BETA-DIOL
• ZYC 1
• 9,11-Estradiol
• 9-DIHYDROESTRADIOL
• DELTA-9(11)-ESTRADIOL
• 9,11-Dehydroestradiol
• Estra-1,3,5(10),9(11)-tetraene-3β,17β-diol

9-Dehydro Estradiol (Estra-1,3,5(10),9(11)-tetraene-3,17β-diol)

CAS: 791-69-5

Phenol-alcohols

Formula: C₁₈H₂₂O₂

Molecular weight: 270.16198

Ref: 45-1A13940

Estradiol Hemihydrate EP Impurity D-d3 (δ-9(11)-Estradiol-d3)

CAS: 791-69-5

Formula: C₁₈H₁₉D₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 273.39

Ref: 4Z-E-0951

Estradiol Hemihydrate EP Impurity D (δ-9(11)-Estradiol)

CAS: 791-69-5

Formula: C₁₈H₂₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 270.37

Ref: 4Z-E-0921

Estra-1,3,5(10),9(11)-tetraene-3,17β-diol (9,11-Didehydroestradiol)

Controlled Product

CAS: 791-69-5

Formula: C₁₈H₂₂O₂

Color and Shape: Neat

Molecular weight: 270.37

Ref: 86-MM0300.02

Estradiol Hemihydrate EP Impurity D-13C2 (δ-9(11)-Estradiol-13C2)

CAS: 791-69-5

Formula: C₁₆₁₃C₂H₂₂O₂

Molecular weight: 272.36

Ref: 4Z-E-09107

∆9(11)-Estradiol

CAS: 791-69-5

Impurity Estradiol EP Impurity D
Applications ∆9(11)-Estradiol (Estradiol EP Impurity D) is a metabolite of Estradiol (E888000).
References Zhu, B., et al.: Steroids, 70, 225 (2005), Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997),

Formula: C₁₈H₂₂O₂

Color and Shape: White To Beige

Molecular weight: 270.37

Ref: TR-E888030

Estradiol Hemihydrate EP Impurity D

CAS: 791-69-5

Formula: C₁₈H₂₂O₂

Molecular weight: 270.37

Ref: ST-EA-CP-E58004

∆9,11-Estradiol-d3

Controlled Product

CAS: 791-69-5

Applications A labelled metabolite of Estradiol (E888000).
References Zhu, B., et al.: Steroids, 70, 225 (2005); Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997);

Formula: C₁₈D₃H₁₉O₂

Color and Shape: Neat

Molecular weight: 273.385

Ref: TR-E888032

Δ9,11-estradiol

Controlled Product

CAS: 791-69-5

Delta9,11-Estradiol is an estrogen that has been found to bind to the estrogen receptor α. The growth factor activity of this drug is mediated through the binding of this receptor and the activation of various intracellular signaling pathways. This drug is effective in treating eye disorders such as macular degeneration. Delta9,11-Estradiol also has a protective effect on ganglion cells by reducing oxidative stress, inhibiting apoptosis, and modulating inflammatory responses. The hydroxyl group in Delta9,11-Estradiol can be used as a corrosion inhibitor in eye drops and other ophthalmic solutions. It binds to viral gene promoters and inhibits transcriptional activity of these genes.

Formula: C₁₈H₂₂O₂

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 270.37 g/mol

Ref: 3D-FE22819