CAS 79112-09-7

1H-Indole-2-carbonyl chloride, 5-fluoro-

Description:

1H-Indole-2-carbonyl chloride, 5-fluoro- is a chemical compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. The presence of a carbonyl chloride functional group indicates that it is an acyl chloride, making it reactive and useful in various chemical reactions, particularly in acylation processes. The 5-fluoro substitution introduces a fluorine atom at the fifth position of the indole ring, which can influence the compound's reactivity, polarity, and biological activity. This compound is typically used in organic synthesis, especially in the development of pharmaceuticals and agrochemicals, due to its ability to serve as an intermediate in the synthesis of more complex molecules. Its reactivity as an acyl chloride allows it to participate in nucleophilic acyl substitution reactions, making it valuable in the formation of amides and esters. Safety precautions should be taken when handling this compound, as carbonyl chlorides can be corrosive and release toxic gases upon hydrolysis.

Formula: C₉H₅ClFNO