CAS 791828-58-5

Methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate

Description:

Methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate, with CAS number 791828-58-5, is a complex organic compound characterized by its spirocyclic structure, which includes a five-membered azaspiro ring. This compound features multiple functional groups, including a carboxylate ester, a hydroxyamino group, and a piperazine moiety, contributing to its potential biological activity. The stereochemistry indicated by the (6S,7S) configuration suggests specific spatial arrangements of atoms, which can significantly influence the compound's interactions with biological targets. The presence of the phenyl group attached to the piperazine ring may enhance lipophilicity, potentially affecting the compound's pharmacokinetics and bioavailability. Overall, this compound's unique structural features and functional groups suggest it may have applications in medicinal chemistry, particularly in the development of therapeutic agents targeting specific biological pathways. Further studies would be necessary to elucidate its biological properties and potential uses.

Formula: C₂₁H₂₈N₄O₅

InChI: InChI=1S/C21H28N4O5/c1-30-20(28)25-14-21(7-8-21)13-16(18(26)22-29)17(25)19(27)24-11-9-23(10-12-24)15-5-3-2-4-6-15/h2-6,16-17,29H,7-14H2,1H3,(H,22,26)/t16-,17-/m0/s1

InChI key: InChIKey=DJXMSZSZEIKLQZ-IRXDYDNUSA-N

SMILES: C(NO)(=O)[C@H]1CC2(CN(C(OC)=O)[C@@H]1C(=O)N3CCN(CC3)C4=CC=CC=C4)CC2

Synonyms:

• (6S,7S)-7-[(Hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylic acid methyl ester
• 5-Azaspiro[2.5]octane-5-carboxylic acid, 7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-, methyl ester, (6S,7S)-
• Incb 007839
• Incb 7839
• Incb007839
• Incb7839
• Methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate
• Aderbasib

Methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate

CAS: 791828-58-5

Formula: C₂₁H₂₈N₄O₅

Purity: 98%

Molecular weight: 416.4708

Ref: IN-DA005A0O

Aderbasib

CAS: 791828-58-5

Aderbasib

Purity: ≥95%

Molecular weight: 416.47g/mol

Ref: 54-BUP21687

Aderbasib

CAS: 791828-58-5

Ref: 7W-GK2672

Aderbasib

CAS: 791828-58-5

Aderbasib (INCB007839) is an ADAM10 and ADAM17 inhibitor with antitumor activity, used in cancer and cardiovascular disease research.

Formula: C₂₁H₂₈N₄O₅

Purity: 97.828%

Color and Shape: Solid

Molecular weight: 416.47

Ref: TM-T40901

Aderbasib

Controlled Product

CAS: 791828-58-5

Dual inhibitor of ADAM10 and ADAM17 metalloproteases

Formula: C₂₁H₂₈N₄O₅

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 416.47 g/mol

Ref: 3D-FA17224

Aderbasib

Controlled Product

CAS: 791828-58-5

Formula: C₂₁H₂₈N₄O₅

Color and Shape: Neat

Molecular weight: 416.471

Ref: TR-A291560