CAS 79236-62-7
:Pyochelin
Description:
Pyochelin is a siderophore produced by certain strains of Pseudomonas aeruginosa, a bacterium known for its role in opportunistic infections. This compound is characterized by its ability to chelate iron, which is crucial for bacterial growth and survival in iron-limited environments. Pyochelin has a unique structure that includes a catechol moiety, which enhances its iron-binding capacity. It is typically produced under low-iron conditions, allowing the bacteria to scavenge iron from the environment effectively. Pyochelin's role extends beyond iron acquisition; it also plays a part in the pathogenicity of Pseudomonas aeruginosa by facilitating the establishment of infections. Additionally, its production can influence the microbial community dynamics in various ecological niches. The compound's potential applications in biotechnology and medicine are being explored, particularly in the context of developing new antimicrobial strategies or as a model for designing synthetic siderophores. Overall, pyochelin exemplifies the intricate relationship between microbial metabolism and environmental adaptation.
Formula:C14H16N2O3S2
InChI:InChI=1S/C14H16N2O3S2/c1-16-10(14(18)19)7-21-13(16)9-6-20-12(15-9)8-4-2-3-5-11(8)17/h2-5,9-10,13,17H,6-7H2,1H3,(H,18,19)/t9-,10+,13-/m1/s1
InChI key:InChIKey=NYBZAGXTZXPYND-GBIKHYSHSA-N
SMILES:CN1[C@](SC[C@H]1C(O)=O)([C@@]2(N=C(SC2)C3=C(O)C=CC=C3)[H])[H]
Synonyms:- (2R,4R)-2-[(4R)-4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolyl]-3-methyl-4-thiazolidinecarboxylic acid
- Pyochelin I
- Pyochelin
- 4-Thiazolidinecarboxylic acid, 2-[(4R)-4,5-dihydro-2-(2-hydroxyphenyl)-4-thiazolyl]-3-methyl-, (2R,4R)-
- Pyocheline
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Found 2 products.
Pyochelin I and Pyochelin II
CAS:Controlled Product<p>Impurity 2.5<br>Applications Pyochelin I and Pyochelin II are the two major siderophores produced and secreted by Pseudomonas aeruginosa PAO1 to assimilate iron. It also has trphenyltin (T809350) decomposition capacity.<br>References Braud, A., et al.: J. Bacteriol., 191, 3517 (2009); Sun, G., et al.: Appl. Environ. Microb., 72, 7264 (2006)<br></p>Formula:C14H16N2O3S2Color and Shape:NeatMolecular weight:324.42
