CAS 79254-98-1

Glycochenodeoxycholic acid 3-glucuronide

Description:

Glycochenodeoxycholic acid 3-glucuronide is a bile acid derivative that plays a significant role in the metabolism and transport of lipids in the body. It is a conjugated bile acid, formed by the glucuronidation of glycochenodeoxycholic acid, which enhances its solubility and facilitates its excretion. This compound is characterized by its hydrophilic properties due to the presence of the glucuronide moiety, which allows it to interact with various biological membranes and transport systems. Glycochenodeoxycholic acid 3-glucuronide is involved in the regulation of cholesterol metabolism and has implications in liver function and bile acid homeostasis. It may also play a role in signaling pathways related to digestion and absorption of dietary fats. The compound is typically studied in the context of liver diseases, metabolic disorders, and its potential therapeutic applications. Its chemical structure includes a steroid nucleus, hydroxyl groups, and a glucuronic acid unit, contributing to its biological activity and pharmacokinetic properties.

Formula: C₃₂H₅₁NO₁₁

InChI: InChI=1S/C32H51NO11/c1-15(4-7-22(35)33-14-23(36)37)18-5-6-19-24-20(9-11-32(18,19)3)31(2)10-8-17(12-16(31)13-21(24)34)43-30-27(40)25(38)26(39)28(44-30)29(41)42/h15-21,24-28,30,34,38-40H,4-14H2,1-3H3,(H,33,35)(H,36,37)(H,41,42)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26+,27-,28+,30-,31+,32-/m1/s1

InChI key: InChIKey=ABFZMYIIUREPLL-ASWJIRIHSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCC(O)=O)=O)C)(CC4)[H])[H])([C@H](O)C[C@@]1(C[C@H](O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)CC2)[H])[H])[H]

Synonyms:

• (3α,5β,7α)-24-[(Carboxymethyl)amino]-7-hydroxy-24-oxocholan-3-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 79254-98-1
• Glycochenodeoxycholic acid 3-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, (3α,5β,7α)-24-[(carboxymethyl)amino]-7-hydroxy-24-oxocholan-3-yl
• (3α,5β,7α)-24-[(Carboxymethyl)amino]-7-hydroxy-24-oxocholan-3-yl β-D-glucopyranosiduronic acid
• β-D-Glucopyranosiduronic acid, (3α,5β,7α)-24-[(carboxymethyl)amino]-7-hydroxy-24-oxocholan-3-yl

Glycochenodeoxycholic Acid 3-Glucuronide

CAS: 79254-98-1

Formula: C₃₂H₅₁NO₁₁

Molecular weight: 625.76

Ref: 4Z-C-5739

Glycochenodeoxycholic-d5 Acid-3-O-b-glucuronide Disodium Salt

Controlled Product

CAS: 75672-22-9, 79254-98-1

Applications Glycochenodeoxycholic-d5 Acid-3-O-β-glucuronide Disodium Salt is an isotope labelled compound of Glycochenodeoxycholic Acid-3-O-β-glucuronide Disodium Salt (G641275), used in steriod studies and also in the synthesis of conjugated and unconjugated bile acids.
References Goto, J., et al.: Chem. Pharm. Bull., 28, 1258 (1980)

Formula: C₃₂H₄₄D₅NNa₂O₁₁

Color and Shape: Neat

Molecular weight: 674.74

Ref: TR-G641277