CAS 79307-93-0
:Azelastine hydrochloride
Description:
Azelastine hydrochloride is a potent antihistamine primarily used in the treatment of allergic rhinitis and conjunctivitis. It is classified as a selective H1 receptor antagonist, which helps alleviate symptoms such as sneezing, itching, and nasal congestion by blocking the action of histamine, a key mediator in allergic responses. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations, including nasal sprays and eye drops. Azelastine hydrochloride exhibits a relatively rapid onset of action, providing relief from allergy symptoms within minutes. Additionally, it has a longer duration of action compared to many other antihistamines, allowing for less frequent dosing. The compound is generally well-tolerated, though some users may experience side effects such as drowsiness or local irritation at the site of application. Its pharmacokinetics indicate that it undergoes extensive metabolism, primarily in the liver, and is excreted mainly through urine. Overall, azelastine hydrochloride is an effective option for managing allergic conditions.
Formula:C22H25Cl2N3O
InChI:InChI=1/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H/t18-;/m1./s1
InChI key:InChIKey=YEJAJYAHJQIWNU-UHFFFAOYSA-N
SMILES:C(C=1C=2C(C(=O)N(N1)C3CCCN(C)CC3)=CC=CC2)C4=CC=C(Cl)C=C4.Cl
Synonyms:- 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, hydrochloride (1:1)
- 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride
- 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride, (S)-
- 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride (1:1)
- A 5610
- Allergodil
- Astelin
- Astepro
- Azelast
- Azeptin
- E 0659
- Optivar
- Rhinolast
- W 2979M
- Zalastine
- Azelastine hydrochloride
- Acelastine hydrochloride
- Adomessen
- 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one hydrochloride
- Optilast
- Aselastine
- Azen
- 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride
- Azepit
- Asutoputin
- 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one
- a5610
- See more synonyms
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Found 18 products.
Azelastine Hydrochloride
CAS:Formula:C22H24ClN3O·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:418.36AZELASTINE HYDROCHLORIDE CRS
CAS:<p>AZELASTINE HYDROCHLORIDE CRS</p>Formula:C22H24ClN3OColor and Shape:White. Crystalline Powder. Powder.Molecular weight:381.8985Azelastine Hydrochloride
CAS:<p>Antihistamines</p>Formula:C22H24ClN3O·HClColor and Shape:White Crystalline PowderMolecular weight:381.160794-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one hydrochloride
CAS:Formula:C22H27Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:420.3753Azelastine hydrochloride
CAS:<p>Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.</p>Formula:C22H24ClN3O·HClPurity:98% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:418.36Azelastine HCl
CAS:Formula:C22H24ClN3O·HClColor and Shape:White To Off-White SolidMolecular weight:381.90 36.46Azelastine hydrochloride, Ph. Eur. grade
CAS:Formula:C22H24ClN3O·HClPurity:≤ 0.1%Color and Shape:White to off-white crystalline powderMolecular weight:418.36Azelastine hydrochloride
CAS:Formula:C22H24ClN3O·HClPurity:(HPLC) ≥ 98.0%Color and Shape:White to off-white powderMolecular weight:418.36Azelastine Hydrochloride
CAS:<p>Applications Orally active H1-hystamine receptor antagonist. Antihistaminic.<br>References Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979), Chand, N., et al.: Int. J. Immunopharmacol., 7, 833 (1985),<br></p>Formula:C22H24ClN3O·ClHColor and Shape:WhiteMolecular weight:418.36Azelastine HCl - Bio-X ™
CAS:<p>Azelastine is an antihistamine drug that is used to treat allergic rhinitis. It inhibits the production of inflammatory mediators such as histamine and leukotrienes. It antagonizes the actions of histamine, resulting in relief of allergy symptoms. Azelastine has been shown to inhibit mediators of mast cell degranulation like leukotrienes in the nasal lavage of patients with rhinitis and possesses mast cell-stabilizing qualities that limit the production of interleukin-6, tryptase, histamine, and TNF-alpha2 from mast cells.</p>Formula:C22H24ClN3O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:418.36 g/molAzelastine HCl
CAS:<p>Histamine-1 receptor antagonist; NF?B activator</p>Formula:C22H25Cl2N3OPurity:Min. 95%Color and Shape:White PowderMolecular weight:418.36 g/mol4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one Hydrochloride
CAS:Formula:C22H25Cl2N3OPurity:≥98%(HPLC)Color and Shape:SolidMolecular weight:418.36
![4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0034HB.jpg&w=3840&q=75)
