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CAS 79352-78-6

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Desethylamodiaquine

Description:
Desethylamodiaquine is a chemical compound that serves as an active metabolite of amodiaquine, a medication primarily used in the treatment of malaria. It is characterized by its antimalarial properties, functioning by inhibiting the growth of Plasmodium parasites in the bloodstream. The compound has a molecular formula that reflects its complex structure, which includes multiple functional groups contributing to its pharmacological activity. Desethylamodiaquine is typically administered in combination with other antimalarial agents to enhance efficacy and reduce the risk of resistance. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are crucial for its therapeutic effectiveness. The compound is known for its relatively long half-life, allowing for sustained action against malaria. Additionally, it may exhibit side effects, which necessitate careful monitoring during treatment. Overall, Desethylamodiaquine plays a significant role in malaria management, particularly in regions where resistance to other antimalarial drugs is prevalent.
Formula:C18H18ClN3O
InChI:InChI=1S/C18H18ClN3O/c1-2-20-11-12-9-14(4-6-18(12)23)22-16-7-8-21-17-10-13(19)3-5-15(16)17/h3-10,20,23H,2,11H2,1H3,(H,21,22)
InChI key:InChIKey=VRXFDHAGFYWGHT-UHFFFAOYSA-N
SMILES:N(C=1C2=C(N=CC1)C=C(Cl)C=C2)C3=CC(CNCC)=C(O)C=C3
Synonyms:
  • 4-[(7-Chloro-4-quinolinyl)amino]-2-[(ethylamino)methyl]phenol
  • Desethylamodiaquine
  • Monodesethylamodiaquine
  • N-Desethylamodiaquine
  • Phenol, 4-[(7-Chloro-4-Quinolinyl)Amino]-2-[(Ethylamino)Methyl]-
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