Tylosin is a macrolide antibiotic primarily used in veterinary medicine, particularly for livestock and poultry. The specific compound "Tylosin, 23-de[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]-" is a derivative of tylosin, characterized by the absence of a specific sugar moiety at the 23-position, which influences its biological activity and pharmacokinetics. It exhibits a complex structure featuring a large lactone ring, which is typical of macrolides, and multiple hydroxyl and methoxy groups that contribute to its solubility and interaction with bacterial ribosomes. Tylosin acts by inhibiting protein synthesis in susceptible bacteria, making it effective against a range of Gram-positive organisms and some Gram-negative bacteria. Its use is associated with concerns regarding antibiotic resistance, leading to regulatory scrutiny in food-producing animals. The compound is typically administered orally or via injection, and its pharmacological profile includes a relatively long half-life, allowing for sustained therapeutic effects. Overall, tylosin and its derivatives are significant in both therapeutic applications and the study of antibiotic mechanisms.

Tylosin, 23-de[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]- (9CI)

79404-97-0: Tylosin is a macrolide antibiotic primarily used in veterinary medicine, particularly for livestock and poultry. The specific compound "Tylosin, 23-de[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]-" is a derivative of tylosin, characterized by the absence of a specific sugar moiety at the 23-position, which influences its biological activity and pharmacokinetics. It exhibits a complex structure featuring a large lactone ring, which is typical of macrolides, and multiple hydroxyl and methoxy groups that contribute to its solubility and interaction with bacterial ribosomes. Tylosin acts by inhibiting protein synthesis in susceptible bacteria, making it effective against a range of Gram-positive organisms and some Gram-negative bacteria. Its use is associated with concerns regarding antibiotic resistance, leading to regulatory scrutiny in food-producing animals. The compound is typically administered orally or via injection, and its pharmacological profile includes a relatively long half-life, allowing for sustained therapeutic effects. Overall, tylosin and its derivatives are significant in both therapeutic applications and the study of antibiotic mechanisms.

<p>23-De(mycinosyloxy)tylosin is a macrolide antibiotic exhibiting activity against Gram-positive bacteria, with limited efficacy against Gram-negative bacteria and mycoplasma.</p>

CAS 79404-97-0

Tylosin, 23-de[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]- (9CI)

23-De(mycinosyloxy)tylosin

Ref: TM-TN10935