CAS 794568-92-6

1-(2-Chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one

Description:

1-(2-Chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one is a synthetic organic compound characterized by its complex structure, which includes a pyrazolo[3,4-d]pyrimidine core. This compound features a chlorophenyl group and a trifluoromethyl-substituted alkyl chain, contributing to its unique chemical properties. It is typically classified as a heterocyclic compound due to the presence of nitrogen atoms in its ring structure. The presence of the trifluoromethyl group enhances its lipophilicity and may influence its biological activity, making it of interest in medicinal chemistry. The compound's potential applications could include roles in pharmaceuticals, particularly in the development of drugs targeting specific biological pathways. Its CAS number, 794568-92-6, allows for easy identification and reference in chemical databases. As with many such compounds, understanding its reactivity, stability, and interactions with biological systems is crucial for assessing its utility in various applications.

Formula: C₁₅H₁₂ClF₃N₄O

InChI: InChI=1S/C15H12ClF3N4O/c1-8(15(17,18)19)6-12-21-13-9(14(24)22-12)7-20-23(13)11-5-3-2-4-10(11)16/h2-5,7-8H,6H2,1H3,(H,21,22,24)/t8-/m1/s1

InChI key: InChIKey=FFPXPXOAFQCNBS-MRVPVSSYSA-N

SMILES: O=C1C2=C(N(N=C2)C3=C(Cl)C=CC=C3)NC(C[C@H](C(F)(F)F)C)=N1

Synonyms:

• BAY 73-6691
• (R)-BAY 73-6691
• 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1-(2-chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-
• 1-(2-Chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one
• BAY 736691

BAY 73-6691

CAS: 794568-92-6

Potent inhibitor of phosphodiesterase type 9 (PDE9), tested in human and murine in vitro assays (IC50 values: 55 nM and 100 nM, respectively). BAY 73-6691 induces long-term potentiation and improves memory in rodents. BAY 73-6691 has been studied as a potential therapy for Alzheimer’s disease.

Formula: C₁₅H₁₂ClF₃N₄O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 356.73 g/mol

Ref: 3D-FB159390

BAY 73-6691

CAS: 794568-92-6

BAY 73-6691 is an inhibitor of brain penetrant PDE9A.

Formula: C₁₅H₁₂ClF₃N₄O

Color and Shape: Solid

Molecular weight: 356.73

Ref: TM-T10481L