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CAS 79516-68-0

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Levocabastine

Description:
Levocabastine is an antihistamine primarily used in the treatment of allergic conditions, particularly allergic rhinitis and conjunctivitis. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, a compound involved in allergic responses. Levocabastine is characterized by its rapid onset of action and relatively long duration of effect, making it suitable for managing symptoms such as sneezing, itching, and nasal congestion. The substance is typically administered topically, either as eye drops or nasal spray, which helps to minimize systemic side effects. Chemically, it is classified as a piperidine derivative, and its structure contributes to its pharmacological properties. Levocabastine is generally well-tolerated, with common side effects including mild drowsiness and local irritation at the site of application. As with any medication, it is important to use Levocabastine under the guidance of a healthcare professional to ensure safety and efficacy, particularly in individuals with pre-existing health conditions or those taking other medications.
Formula:C26H29FN2O2
InChI:InChI=1S/C26H29FN2O2/c1-19-17-29(16-15-26(19,24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,14-12-23)20-7-9-22(27)10-8-20/h2-10,19,23H,11-17H2,1H3,(H,30,31)/t19-,23-,25-,26-/m1/s1
InChI key:InChIKey=ZCGOMHNNNFPNMX-KYTRFIICSA-N
SMILES:C(O)(=O)[C@]1([C@H](C)CN(CC1)[C@@H]2CC[C@](C#N)(CC2)C3=CC=C(F)C=C3)C4=CC=CC=C4
Synonyms:
  • (3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid
  • (3S,4R)-1-[cis-4-Cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid
  • 4-Piperidinecarboxylic acid, 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-, (3S-(1(cis),3alpha,4beta))-
  • 4-Piperidinecarboxylic acid, 1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-, [3S-[1(cis),3α,4β]]-
  • 4-Piperidinecarboxylic acid, 1-[cis-4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-, (3S,4R)-
  • Levocabastina
  • Levocabastina [Spanish]
  • Levocabastine [INN:BAN]
  • Levocabastinum
  • Levocabastinum [Latin]
  • See more synonyms
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