CAS 79517-01-4

Octreotide

Description:

Octreotide is a synthetic octapeptide analog of somatostatin, a naturally occurring hormone that inhibits the secretion of several other hormones and substances in the body. It is primarily used in the medical field for its ability to reduce growth hormone levels and manage conditions such as acromegaly, certain types of tumors, and severe diarrhea associated with neuroendocrine tumors. Octreotide exhibits a high affinity for somatostatin receptors, particularly subtype 2, which contributes to its therapeutic effects. The compound is typically administered via subcutaneous or intravenous routes and has a longer half-life compared to natural somatostatin, allowing for less frequent dosing. In terms of physical properties, octreotide is a white to off-white powder that is soluble in water and exhibits stability under appropriate storage conditions. Its molecular structure includes a cyclic disulfide bond, which enhances its resistance to enzymatic degradation, making it effective for clinical use. Overall, octreotide represents a significant advancement in the management of hormone-related disorders.

Formula: C₄₉H₆₆N₁₀O₁₀S₂

InChI: InChI=1/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29?,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1

Synonyms:

• Ccris 8708
• D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide acetate (salt)
• D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2-7)-disulfide acetate (salt)
• L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2-7)-disulfide, (R-(R*,R*))-, acetate (salt)
• (Preservative Free)
• Sms 201-995
• Sandostatin
• Sandostatin LAR
• Sandostatin LAR Depot
• Unii-75R0U2568I
• (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate (1:1)

Octreotide

CAS: 79517-01-4

Octreotide is a longer acting synthetic octapeptide analog of the naturally occurring hormone somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormones. Melacini et al. studied the conformation of the peptide in solution by NMR. CAS Number (net): 83150-76-9.

Formula: C₄₉H₆₆N₁₀O₁₀S₂

Purity: ≥ 99.5%

Color and Shape: White

Molecular weight: 1019.26

Ref: 01-4042822

OCTREOTIDE CRS

CAS: 79517-01-4

OCTREOTIDE CRS

Ref: 41-Y0002104

Octreotide Acetate

CAS: 79517-01-4

Formula: C₅₁H₇₀N₁₀O₁₂S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 1079.2913

Ref: IN-DA019FSF

Octreotide Acetate

CAS: 79517-01-4

Octreotide Acetate

Purity: ≥98%

Molecular weight: 1079.3g/mol

Ref: 54-BUP10206

Octreotide acetate

CAS: 79517-01-4

Formula: C₄₉H₆₆N₁₀O₁₀S₂·x(CH₃COOH)

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 1019.24 (free acid)

Ref: 7W-GP4360

Octreotide Acetate

CAS: 79517-01-4

Formula: C₄₉H₆₆N₁₀O₁₀S₂

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1019.24

Ref: BP-BPPG052

Octreotide Acetate

CAS: 79517-01-4

Octreotide Acetate (Sandostatin) is a potent, long-acting synthetic somatostatin octapeptide analog that inhibits secretion of growth hormone.

Formula: C₅₁H₇₀N₁₀O₁₂S₂

Purity: 99.03% - 99.87%

Color and Shape: Less To Off-White Lyophilised Solid Colourless To Off-White Lyophilised Solid

Molecular weight: 1079.3

Ref: TM-T4119

Octreotide Acetate

CAS: 79517-01-4

Formula: C₄₉H₆₆N₁₀O₁₀S₂·2C₂H₄O₂

Molecular weight: 1019.25 2 60.05

Ref: 4Z-PO-036002

Octreotide Acetate

CAS: 79517-01-4

Applications Octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly.
References Bauer, W., et al.: Life Sci., 31, 1133 (1982), Plewe, G., et al.: Lancet, 2, 782 (1984), Kraenzlin, M.E., et al.: Experientia, 41, 738 (1985), del Pozo, E., et al.: Acta Endocrinol., 111, 433 (1986),

Formula: C₄₉H₆₆N₁₀O₁₀S₂·C₂H₄O₂

Color and Shape: White To Off-White

Molecular weight: 1079.29

Ref: TR-O239950

Octreotide acetate

CAS: 79517-01-4

Octapeptide analog of Somatostatin; inhibits insulin and growth hormones

Formula: C₄₉H₆₆N₁₀O₁₀S₂·xCH₃COOH

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 1,019.24 g/mol

Ref: 3D-FO26520

Octreotide Acetate

CAS: 79517-01-4

Purity: 99%

Molecular weight: 1079.300049

Ref: 10-F864034

Octreotide Acetate

CAS: 79517-01-4

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Formula: C₄₉H₆₆N₁₀O₁₀S₂·xC₂H₄O₂

Color and Shape: White Powder

Molecular weight: 1018.44048

Ref: 45-1477604