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CAS 79551-86-3

:

20-Hydroxy arachidonic acid

Description:
20-Hydroxy arachidonic acid (20-HETE) is a biologically active metabolite of arachidonic acid, primarily involved in various physiological processes, including vascular function and inflammation. It is characterized by its hydroxyl group at the 20th carbon position of the arachidonic acid chain, which is a polyunsaturated fatty acid. This modification alters its reactivity and biological activity compared to its parent compound. 20-HETE is known to act as a signaling molecule, influencing processes such as vasoconstriction, cell proliferation, and apoptosis. It is synthesized through the action of cytochrome P450 enzymes, particularly CYP4A and CYP4F, and is found in various tissues, including the kidneys and the brain. The substance has garnered interest in research due to its role in cardiovascular health and potential implications in diseases such as hypertension and cancer. Its CAS number, 79551-86-3, is used for identification in chemical databases and regulatory contexts. Overall, 20-HETE is a significant compound in the study of lipid mediators and their effects on human health.
Formula:C20H32O3
InChI:InChI=1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
InChI key:InChIKey=NNDIXBJHNLFJJP-DTLRTWKJSA-N
SMILES:C(=C\C/C=C\C/C=C\CCCCCO)\C/C=C\CCCC(O)=O
Synonyms:
  • (5Z,8Z,11Z,14Z)-20-Hydroxy-5,8,11,14-eicosatetraenoic acid
  • (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid
  • 20-Hete
  • 20-Hydroxy-5,8,11,14-eicosatetraenoic acid
  • 20-Hydroxyarachidonic acid
  • 20-Hydroxyeicosa-5Z,8Z,11Z,14Z-tetraenoic acid
  • 20-Hydroxyeicosatetraenoic acid
  • 5,8,11,14-Eicosatetraenoic acid, 20-hydroxy-, (5Z,8Z,11Z,14Z)-
  • 5,8,11,14-Eicosatetraenoic acid, 20-hydroxy-, (all-Z)-
  • ω-Hydroxyarachidonic acid
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