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CAS 79561-22-1

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6-D-Ala-10-D-gly-LHRH-ethylamide

Description:
6-D-Ala-10-D-gly-LHRH-ethylamide, also known by its CAS number 79561-22-1, is a synthetic analog of the naturally occurring gonadotropin-releasing hormone (GnRH). This compound is characterized by specific modifications to its amino acid sequence, which enhance its stability and biological activity compared to native GnRH. The substitution of D-amino acids, such as D-alanine and D-glycine, contributes to increased resistance to enzymatic degradation, making it a valuable tool in research and potential therapeutic applications. The ethylamide modification at the C-terminus further enhances its potency and receptor binding affinity. This peptide is primarily studied for its role in regulating reproductive hormones and has implications in treating conditions related to hormone imbalances, such as certain cancers and infertility. Its unique structure allows for targeted interactions with GnRH receptors, making it a subject of interest in pharmacological research. Overall, 6-D-Ala-10-D-gly-LHRH-ethylamide exemplifies the advancements in peptide design aimed at improving therapeutic efficacy.
Formula:C56H78N16O12C2H4O2
InChI:InChI=1/C56H78N16O12.2C2H4O2/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15-32)68-53(82)44(28-73)71-51(80)42(24-33-26-62-37-11-7-6-10-36(33)37)69-52(81)43(25-34-27-59-29-63-34)70-48(77)38-18-19-46(75)65-38;2*1-2(3)4/h6-7,10-11,14-17,26-27,29-31,38-45,62,73-74H,5,8-9,12-13,18-25,28H2,1-4H3,(H,59,63)(H,60,83)(H,64,78)(H,65,75)(H,66,79)(H,67,76)(H,68,82)(H,69,81)(H,70,77)(H,71,80)(H4,57,58,61);2*1H3,(H,3,4)/t31-,38?,39+,40+,41+,42+,43+,44+,45+;;/m1../s1
Synonyms:
  • LHRH, ala(6)-gly(10)-ethylamide-
  • 10-Des-gly,6-(D-ala)-LHRH ethylamide, acetate salt
  • Ala(6)-gly(10)-gnrh
  • LHRH, alanine(6)-glycine(10)-ethylamide-
  • Lhrh-A
  • des-Gly(sup 10),(D-Ala(sup 6))-LHRH-ethylamide
  • Luteinizing hormone-releasing factor(pig),
  • 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, diacetate (salt)
  • AlarelinAcetate
  • Alarelin Acetate
  • See more synonyms
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