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CAS 79578-39-5

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BetaMethasone 9,11-Epoxide 17-Propionate

Description:
Beta-Methasone 9,11-Epoxide 17-Propionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from betamethasone, a potent glucocorticoid, and features an epoxide group at the 9,11 positions, which enhances its biological activity. The 17-propionate esterification improves its solubility and absorption, making it suitable for therapeutic applications. This compound is typically used in the treatment of various inflammatory conditions, including skin disorders, allergies, and autoimmune diseases. Its mechanism of action involves the modulation of gene expression, leading to decreased production of pro-inflammatory cytokines and mediators. As with other corticosteroids, potential side effects may include adrenal suppression, metabolic changes, and increased susceptibility to infections. Proper dosing and monitoring are essential to minimize adverse effects while maximizing therapeutic benefits. Overall, Beta-Methasone 9,11-Epoxide 17-Propionate exemplifies the utility of synthetic modifications in enhancing the efficacy and safety profile of corticosteroids in clinical practice.
Formula:C25H32O6
Synonyms:
  • (4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl propionate
  • Beclomethasone Propionate Impurity U
  • Beclomethasone dipropionate EP Impurity U
  • Beclometasone Dipropionate EP Impurity U
  • Beclomethasone Dipropionate Impurity 3
  • Beclomethasone EP Impurity U
  • Beclomethasone Impurity 17(Beclometasone Dipropionate EP Impurity U)
  • 9,11β-Epoxy-21-hydroxy-16β-methyl-3,20-dioxo-9β-pregna-1,4-dien-17-yl propanoate
  • (9β,11β,16β)-9,11-Epoxy-21-hydroxy-16-Methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • BetaMethasone 9,11-Epoxide 17-Propionate
  • See more synonyms
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