CAS 79598-49-5

2-(2-Azidoethoxy)acetyl chloride

Description:

2-(2-Azidoethoxy)acetyl chloride, with the CAS number 79598-49-5, is an organic compound characterized by the presence of an azido group (-N3) and an acetyl chloride functional group. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly due to the presence of the acetyl chloride moiety, which can readily participate in nucleophilic acyl substitution reactions. The azido group contributes to its potential as a versatile intermediate in organic synthesis, especially in the preparation of various nitrogen-containing compounds. It is important to handle this substance with care, as both the azido and acyl chloride functionalities can pose hazards, including toxicity and reactivity with moisture, leading to the release of hydrochloric acid. Proper safety protocols should be followed when working with this compound, including the use of personal protective equipment and working in a well-ventilated area or fume hood.

Formula: C₄H₆ClN₃O₂

InChI: InChI=1S/C4H6ClN3O2/c5-4(9)3-10-2-1-7-8-6/h1-3H2

InChI key: InChIKey=FSOUWBZLOHCVTL-UHFFFAOYSA-N

SMILES: O(CCN=[N+]=[N-])CC(Cl)=O

Synonyms:

• Acetyl chloride, (2-azidoethoxy)-
• 2-(2-Azidoethoxy)acetyl chloride
• Acetyl chloride, 2-(2-azidoethoxy)-
• 2-Azidoethoxyacetyl chloride

Azido-PEG1-CH2COO-Cl

CAS: 79598-49-5

Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker, commonly employed in the synthesis of PROTAC BRD4 Degrader-1[1].

Formula: C₄H₆ClN₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 163.56

Ref: TM-T17477