CAS 79598-53-1

6-azido-Hexanoic acid

Description:

6-Azido-hexanoic acid is an organic compound characterized by the presence of an azido group (-N3) attached to a hexanoic acid backbone. This compound features a six-carbon chain with a carboxylic acid functional group at one end and an azido group at the sixth carbon. The azido group is known for its reactivity, particularly in click chemistry applications, making 6-azido-hexanoic acid useful in bioconjugation and polymer chemistry. The presence of both the carboxylic acid and azido functionalities allows for diverse chemical modifications, enabling the synthesis of various derivatives. Additionally, the compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the carboxylic acid group. Safety considerations are important when handling azido compounds, as they can be sensitive to heat and shock, potentially leading to explosive decomposition. Overall, 6-azido-hexanoic acid serves as a valuable intermediate in synthetic organic chemistry and materials science.

Formula: C₆H₁₁N₃O₂

Synonyms:

• Hexanoic acid, 6-azido-
• 6-Azidohexanoic acid
• 6-Azido-Hexanoic Acid
• 6-Azidohexanoic acid - A1945
• e-Azidocaproic acid
• 6-Azidohexanoic acid >=95%

6-Azido-hexanoic acid

CAS: 79598-53-1

Formula: C₆H₁₁N₃O₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 157.1704

Ref: IN-DA00G3CY

6-Azidohexanoic acid

CAS: 79598-53-1

6-Azidohexanoic acid

Purity: 98%

Molecular weight: 157.17g/mol

Ref: 54-BICR249

6-azido-hexanoic acid

CAS: 79598-53-1

Formula: C6H11N3O2

Purity: >98%

Color and Shape: Liquid

Molecular weight: 157.17

Ref: 48-10-5006

6-Azidohexanoic Acid

Controlled Product

CAS: 79598-53-1

Applications 6-Azidohexanoic Acid is a reagent that is useful for click chemistry.
References Alleti, R.,et al.: J. Org. Chem., 75, 5895 (2010); Daumar, P., et al.: Bioconjug. Chem., 23, 1557 (2012)

Formula: C₆H₁₁N₃O₂

Color and Shape: Neat

Molecular weight: 157.17

Ref: TR-A850030

6-Azido-Hexanoic Acid

CAS: 79598-53-1

6-Azido-Hexanoic Acid is a lysine derivative that is used for Click Chemistry, which involves the use of reactive nitrenes, such as azides, to create stable covalent bonds with other molecules. This product is also used in diagnostic agents and has shown anticancer activity against prostate cancer cells. 6-Azido-Hexanoic Acid can be synthesized using Click Chemistry and x-ray crystal structures have been determined. The structure consists of a cyclic peptide that contains an amide bond between two lysine residues. The compound has a neutral pH and can be detected by gravimetric analysis.

Formula: C₆H₁₁N₃O₂

Purity: Min. 95%

Molecular weight: 157.17 g/mol

Ref: 3D-AHA-1904-PI

6-Azido-hexanoic acid

CAS: 79598-53-1

6-Azido-hexanoic acid is a growth factor that inhibits the binding of TGF-β to its receptor. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. 6-Azido-hexanoic acid binds with high affinity to the acidic region of TGF-β, preventing it from binding to its receptor. This molecule also inhibits the activation of the TGF-β receptor complex by decreasing the phosphorylation of Smad 1/5/8. 6-Azido-hexanoic acid has been shown to be effective in pancreatic cancer models and control studies have demonstrated an absence of toxicity or side effects.

Formula: C₆H₁₁N₃O₂

Purity: Min. 97.0 Area-%

Color and Shape: Powder

Molecular weight: 157.17 g/mol

Ref: 3D-FA55794

6-Azido-hexanoic acid

CAS: 79598-53-1

Formula: C₆H₁₁N₃O₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 157.173

Ref: 10-F494252

6-Azidohexanoic Acid

CAS: 79598-53-1

6-Azidohexanoic acid, a six-carbon saturated fatty acid featuring an ω-terminal azide group, serves as a versatile linker for bioconjugation via copper(I)-catalyzed cycloaddition reactions (click chemistry). This functionality enables its initial acylation to a compound, forming a derivative that can subsequently be conjugated to another compound through click chemistry, facilitating the synthesis of complex molecules.

Formula: C₆H₁₁N₃O₂

Color and Shape: Solid

Molecular weight: 157.173

Ref: TM-T84438

6-Azido-hexanoic acid

CAS: 79598-53-1

Building block for Staudinger ligation as well as for “click chemistry”. This highly selective reaction can be applied for the conjugation of peptides with various molecules and for the cyclization of peptides. The azido moiety may also be considered as a protected amino group which is deblocked under reductive conditions.

Formula: C₆H₁₁N₃O₂

Purity: 99.2%

Color and Shape: Colourless Oily

Molecular weight: 157.17

Ref: 01-4066756