CAS 79640-85-0

(6aR)-5,6,6a,7-Tetrahydro-6-propyl-4H-dibenzo[de,g]quinoline-2,10,11-triol hydrobromide (1:1)

Description:

The chemical substance known as (6aR)-5,6,6a,7-Tetrahydro-6-propyl-4H-dibenzo[de,g]quinoline-2,10,11-triol hydrobromide (1:1) is a complex organic compound characterized by its unique dibenzoquinoline structure, which features a fused ring system. This compound contains multiple functional groups, including hydroxyl (-OH) groups, which contribute to its potential biological activity and solubility properties. The presence of a propyl group enhances its hydrophobic characteristics, influencing its interaction with biological membranes. As a hydrobromide salt, it is typically more soluble in water compared to its free base form, which can facilitate its use in pharmaceutical applications. The stereochemistry indicated by the (6aR) designation suggests specific spatial arrangements of atoms, which can significantly affect the compound's pharmacological properties. Overall, this substance may exhibit interesting pharmacological activities, making it a subject of interest in medicinal chemistry and drug development, although specific biological effects would require further investigation.

Formula: C₁₉H₂₁NO₃·BrH

InChI: InChI=1S/C19H21NO3.BrH/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14;/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3;1H/t15-;/m1./s1

InChI key: InChIKey=KIAIFHTWTMKEDI-XFULWGLBSA-N

SMILES: C(CC)N1[C@]2(C=3C(C=4C(C2)=CC=C(O)C4O)=CC(O)=CC3CC1)[H].Br

Synonyms:

• (6aR)-5,6,6a,7-Tetrahydro-6-propyl-4H-dibenzo[de,g]quinoline-2,10,11-triol hydrobromide (1:1)
• 4H-Dibenzo[de,g]quinoline-2,10,11-triol, 5,6,6a,7-tetrahydro-6-propyl-, hydrobromide, (6aR)-
• 4H-Dibenzo[de,g]quinoline-2,10,11-triol, 5,6,6a,7-tetrahydro-6-propyl-,hydrobromide, (R)-
• 4H-Dibenzo[de,g]quinoline-2,10,11-triol,5,6,6a,7-tetrahydro-6-propyl-, hydrobromide, (6aR)- (9CI)
• TNPA-HBr
• 4H-Dibenzo[de,g]quinoline-2,10,11-triol, 5,6,6a,7-tetrahydro-6-propyl-, hydrobromide (1:1), (6aR)-

R(-)-2-Hydroxy-N-propylnorapomorphine Hydrobromide Salt

Controlled Product

CAS: 79640-85-0

Applications The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. R(-)-2,10,11-Trihydroxy-N-propyl-noraporphine Hydrobromide is a potent and selective D2 dopamine receptor agonist (2).
References (1) Ptácek, R., et al.: Med Sci Monit. 17, RA215 (2011) (2) Gao, Y. G., et al.: J Med Chem. 33, 1800 (1990)

Formula: C₁₉H₂₁NO₃·HBr

Color and Shape: Neat

Molecular weight: 392.28

Ref: TR-R701253