CAS 79672-88-1

Piriprost

Description:

Piriprost, with the CAS number 79672-88-1, is a chemical compound that belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily recognized for its role as a selective inhibitor of the enzyme cyclooxygenase (COX), which is involved in the biosynthesis of prostaglandins, mediators of inflammation and pain. Piriprost exhibits anti-inflammatory, analgesic, and antipyretic properties, making it useful in the management of various inflammatory conditions. The compound is characterized by its ability to selectively inhibit COX-2 over COX-1, which may result in a reduced risk of gastrointestinal side effects commonly associated with traditional NSAIDs. Additionally, Piriprost has been studied for its potential therapeutic effects in conditions such as arthritis and other inflammatory diseases. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion, contributes to its efficacy and safety profile, although specific details may vary based on formulation and administration routes. Overall, Piriprost represents a significant advancement in the development of targeted anti-inflammatory therapies.

Formula: C₂₆H₃₅NO₄

InChI: InChI=1/C26H35NO4/c1-2-3-5-13-21(28)15-16-22-23-17-20(12-8-9-14-26(30)31)27(24(23)18-25(22)29)19-10-6-4-7-11-19/h4,6-7,10-11,15-17,21-22,25,28-29H,2-3,5,8-9,12-14,18H2,1H3,(H,30,31)/b16-15+/t21-,22+,25+/m0/s1

Synonyms:

• Piriprost [USAN:INN]
• (4R,5R)-1,4,5,6-Tetrahydro-5-hydroxy-4-((E)-(3S)-3-hydroxy-1-octenyl)-1-phenylcyclopenta(b)pyrrole-2-valeric acid
• Cyclopenta(b)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenyl-, (4R-(4alpha(1E,3S*),5beta))-
• Piriprostium
• Piriprostium [Latin]
• U-60,257
• Unii-R802O5Nilk
• Cyclopenta(b)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-((1E,3S)-3-hydroxy-1-octenyl)-1-phenyl-, (4R,5R)-
• 5-{(4R,5R)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-1-phenyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrol-2-yl}pentanoic acid

Piriprost

CAS: 79672-88-1

Piriprost inhibits leukotrienes, reduces smoke-induced alveolar permeability, decreases plasminogen activator activity, and swells type I alveolar cells.

Formula: C₂₆H₃₅NO₄

Color and Shape: Solid

Molecular weight: 425.56

Ref: TM-T68682