CAS 797-63-7

Levonorgestrel

Description:

Levonorgestrel is a synthetic progestin, primarily used in hormonal contraceptives and emergency contraception. It is characterized by its ability to inhibit ovulation, thicken cervical mucus, and alter the endometrial lining, thereby preventing pregnancy. Chemically, it is a derivative of norethisterone and belongs to the class of compounds known as 19-nortestosterone derivatives. Levonorgestrel is typically administered in various forms, including oral tablets, intrauterine devices (IUDs), and implants. Its molecular formula is C21H28O2, and it has a relatively high lipophilicity, which contributes to its effectiveness and duration of action in the body. The substance is generally well-tolerated, but it can have side effects such as nausea, headache, and changes in menstrual bleeding patterns. Levonorgestrel is also used in combination with estrogen in some contraceptive formulations. Its mechanism of action and pharmacokinetics make it a crucial component in reproductive health management.

Formula: C₂₁H₂₈O₂

InChI: InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1

InChI key: InChIKey=WWYNJERNGUHSAO-XUDSTZEESA-N

SMILES: C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (-)-Norgestrel
• (14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
• (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
• 13-Ethyl-17-Alpha-Ethynyl-17-Beta-Hydroxy-4-Gonen-3-One
• 13-Ethyl-17-Alpha-Ethynylgon-4-En-17-Beta-Ol-3-One
• 13-Ethyl-17-Hydroxy-19-Dinor-17-Alpha-Pregn-4-En-20-Yn-3-On(+)-1
• 13-Ethyl-17-ethynyl-17β-hydroxy-4-gonen-3-one
• 13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one
• 13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one
• 13-Ethyl-17α-ethynylgon-4-en-17β-ol-3-one
• 13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
• 17-Alpha-Ethinyl-13-Beta-Ethyl-17-Beta-Hydroxy-4-Estren-3-One
• 17-Beta-Hydroxy-18-Methyl-19-Nor-17-Alpha-Pregn-4-En-20-Yn-3-One
• 17-Ethynyl-18-Methyl-19-Nortestosteron
• 17-Ethynyl-18-Methyl-19-Nortestosterone
• 17α-Ethynyl-13-ethyl-19-nortestosterone
• 17α-Ethynyl-13β-ethyl-3-oxo-4-estren-17β-ol
• 17α-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one
• 17α-Ethynyl-18-homo-19-nortestosterone
• 17α-Ethynyl-18-methyl-19-nortestosterone
• 17β-Hydroxy-18-methyl-19-nor-17α-pregn-4-en-20-yn-3-one
• 18,19-Dinor-17α-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-
• 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-
• 18-Methyl-17-Alpha-Ethynyl-19-Nortestosterone
• 18-Methyl-17α-ethynyl-19-nortestosterone
• 18-Methylnorethindrone
• 19-Nortestosterone, 17-ethynyl-18-methyl-
• <span class="text-smallcaps">D</span>-(-)-Norgestrel
• D-(-)-Norgestrel
• Dexnorgestrel
• Femilis
• Femilis Slim
• Follistrel
• Jadelle
• Jaydess
• Levonorgestrel
• Levonova
• Lng-IUS
• Microlut
• Microluton
• Microval
• Mirena
• Norgeston
• Norgestrel (L-)
• Norgestrelem
• Norlevo
• Norplant
• Norplant 2
• Norplant II
• Plan B One-Step
• Postinor 2
• Sino-implant (II)
• Skyla
• Wy 5104

D-(-)-Norgestrel - Bio-X ™

Controlled Product

CAS: 797-63-7

D-(-)-Norgestrel is a synthetic progesterone analog and has been shown to have high affinity for progesterone receptors, making it effective in preventing pregnancy by inhibiting ovulation and thickening the cervical mucus to prevent sperm from reaching the egg. D-(-)-Norgestrel also contains an alkyne group, making it a useful click chemistry reagent, and is an antioxidant in vivo.
This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₁H₂₈O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 312.45 g/mol

Ref: 3D-BN300105

D-(-)-Norgestrel

Controlled Product

CAS: 797-63-7

D-(-)-Norgestrel is a progestin having similar effects to those of the hormone progesterone

Formula: C₂₁H₂₈O₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 312.45 g/mol

Ref: 3D-FN26454

(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one

CAS: 797-63-7

Formula: C₂₁H₂₈O₂

Purity: 99+%

Molecular weight: 312.453

Ref: 10-F358122

D-(-)-Norgestrel Sulfate Sodium Salt

Controlled Product

CAS: 797-63-7

Stability Hygroscopic
Applications A metabolite of Norgestrel.

Formula: C₂₁H₂₇NaO₅S

Color and Shape: Neat

Molecular weight: 414.491

Ref: TR-N689520

Levonorgestrel

CAS: 797-63-7

Color and Shape: Neat

Ref: 61-FOR0121.00