CAS 79778-41-9

Neridronate

Description:

Neridronate is a bisphosphonate compound primarily used in the treatment of bone disorders, particularly osteoporosis and Paget's disease. It functions by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain bone density and strength. The chemical structure of neridronate features a central phosphorus atom bonded to two hydroxyethyl groups and two phosphonate groups, which contribute to its biological activity. It is typically administered intravenously and has a relatively long half-life in the body, allowing for less frequent dosing compared to some other bisphosphonates. Neridronate is known for its efficacy in reducing the risk of fractures in patients with osteoporosis and is also used in the management of bone pain associated with metastatic cancer. Common side effects may include gastrointestinal disturbances and, in rare cases, osteonecrosis of the jaw. Overall, neridronate represents an important therapeutic option in the management of various bone-related conditions.

Formula: C₆H₁₇NO₇P₂

InChI: InChI=1S/C6H17NO7P2/c7-5-3-1-2-4-6(8,15(9,10)11)16(12,13)14/h8H,1-5,7H2,(H2,9,10,11)(H2,12,13,14)

InChI key: InChIKey=PUUSSSIBPPTKTP-UHFFFAOYSA-N

SMILES: C(CCCCCN)(P(=O)(O)O)(P(=O)(O)O)O

Synonyms:

• (6-Amino-1-Hydroxyhexane-1,1-Diyl)Bis(Phosphonic Acid)
• (6-Amino-1-hydroxyhexane-1,1-diyl)diphosphonic acid
• (6-Amino-1-hydroxyhexylidene)diphosphonic acid
• 6-Amino-1-hydroxyhexane-1,1-diphosphonate
• 6-Amino-1-hydroxyhexane-1,1-diphosphonic acid
• 6-Amino-1-hydroxyhexylidene-1,1-bis(phosphonic acid)
• 6-Amino-1-hydroxyhexylidenediphosphonic acid
• Acide neridronique
• Acide neridronique [INN-French]
• Acido neridronico
• Acido neridronico [INN-Spanish]
• Acidum neridronicum
• Acidum neridronicum [INN-Latin]
• Neridronate
• Neridronic acid [INN]
• Nerixia
• P,P′-(6-Amino-1-hydroxyhexylidene)bis[phosphonic acid]
• Phosphonic acid, (6-amino-1-hydroxyhexylidene)bis-
• Phosphonic acid, P,P′-(6-amino-1-hydroxyhexylidene)bis-

Neridronate

CAS: 79778-41-9

Neridronate

Purity: ≥98%

Molecular weight: 277.15g/mol

Ref: 54-BUP21142

Neridronate

CAS: 79778-41-9

Formula: C₆H₁₇NO₇P₂

Molecular weight: 277.15

Ref: 7W-GP3862

Neridronate

CAS: 79778-41-9

Neridronate is an aminodiphosphate that disorders of bone metabolism and complex regional pain syndromes (CRPS) (OI) (PDB).

Formula: C₆H₁₇NO₇P₂

Purity: 99.91%

Color and Shape: White Solid

Molecular weight: 277.15

Ref: TM-T13794

(6-Amino-1-hydroxyhexane-1,1-diyl)diphosphonic acid

CAS: 79778-41-9

Purity: 95.0%

Molecular weight: 277.1499938964844

Ref: 10-F461292

Neridronate

CAS: 79778-41-9

Inhibits osteoclast resorption; anti-hypercalcemic

Formula: C₆H₁₇NO₇P₂

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 277.15 g/mol

Ref: 3D-FN16041