CAS 79786-01-9

Casuarinin

Description:

Casuarinin is a naturally occurring compound primarily found in the Casuarina species, particularly in the bark and leaves. It belongs to the class of polyphenols, which are known for their antioxidant properties. Casuarinin exhibits a range of biological activities, including anti-inflammatory, antimicrobial, and potential anticancer effects, making it of interest in pharmacological research. The compound is characterized by its ability to scavenge free radicals, which contributes to its protective effects against oxidative stress. Additionally, Casuarinin has been studied for its role in traditional medicine, particularly in the treatment of various ailments. Its chemical structure features multiple hydroxyl groups, which enhance its reactivity and interaction with biological systems. As research continues, Casuarinin's potential applications in health and medicine are being explored, highlighting its significance in both natural product chemistry and therapeutic development.

Formula: C₄₁H₂₈O₂₆

InChI: InChI=1S/C41H28O26/c42-11-1-7(2-12(43)23(11)47)37(58)64-16-6-63-38(59)8-3-13(44)24(48)27(51)17(8)18-9(4-14(45)25(49)28(18)52)39(60)65-34(16)36-35-32(56)22-21(41(62)66-35)20(30(54)33(57)31(22)55)19-10(40(61)67-36)5-15(46)26(50)29(19)53/h1-5,16,32,34-36,42-57H,6H2

InChI key: InChIKey=MMQXBTULXAEKQE-UHFFFAOYSA-N

SMILES: O=C1C=2C=3C=4C(C(=O)OC(C(C(O)C2C(O)=C(O)C3O)O1)C5C(OC(=O)C6=CC(O)=C(O)C(O)=C6)COC(=O)C=7C(C=8C(C(=O)O5)=CC(O)=C(O)C8O)=C(O)C(O)=C(O)C7)=CC(O)=C(O)C4O

Synonyms:

• Casuarinin
• Neovescalin, 11-de(6-carboxy-2,3,4-trihydroxyphenyl)-, cyclic 16,18-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 17-(3,4,5-trihydroxybenzoate), (15β)-
• 7H-Dibenzo[g,i][1,5]dioxacycloundecin, neovescalin deriv.
• 4,7-Methanodibenzo[f,h][1,4]dioxecin, neovescalin deriv.

Casuarinin

Controlled Product

CAS: 79786-01-9

Casuarinin is a natural product that is found in the leaves of the Indian tree, Caesalpinia sappan. It has been shown to have an apoptotic effect on tumor cells and inflammatory skin diseases. Casuarinin binds to TNF-α induced hydroxyl group metabolic rate receptors on basophilic leukemia and carcinoma cell lines, which leads to a decrease in the production of proinflammatory cytokines. Casuarinin is also active against inflammatory skin diseases such as atopic dermatitis and psoriasis. The mechanism of action may be due to its ability to inhibit the release of histamine from mast cells, thereby suppressing inflammation.

Formula: C₄₁H₂₈O₂₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 936.6 g/mol

Ref: 3D-FC178845

Casuarinin

CAS: 79786-01-9

Casuarinin, an ellagitannin found in pomegranates and certain Casuarina/Stachyurus plants, is a carbonic anhydrase inhibitor and astringent.

Formula: C₄₁H₂₈O₂₆

Color and Shape: Solid

Molecular weight: 936.65

Ref: TM-T68681