CAS 79795-25-8

5-methoxy-2-methylnaphthalen-1-ol

Description:

5-Methoxy-2-methylnaphthalen-1-ol, with the CAS number 79795-25-8, is an organic compound belonging to the naphthalene family, characterized by a naphthalene backbone substituted with a methoxy group and a hydroxyl group. This compound typically appears as a solid or viscous liquid, depending on its purity and temperature. It is known for its aromatic properties, which can contribute to its potential applications in fragrance and flavor industries. The presence of the hydroxyl group indicates that it can participate in hydrogen bonding, influencing its solubility in polar solvents. Additionally, the methoxy group can affect the compound's reactivity and stability, making it of interest in various chemical syntheses. Its structural features may also impart biological activity, warranting investigation in pharmacological contexts. Overall, 5-methoxy-2-methylnaphthalen-1-ol is a compound of interest in both synthetic organic chemistry and potential applications in medicinal chemistry.

Formula: C₁₂H₁₂O₂

InChI: InChI=1/C12H12O2/c1-8-6-7-9-10(12(8)13)4-3-5-11(9)14-2/h3-7,13H,1-2H3

SMILES: Cc1ccc2c(cccc2OC)c1O

Synonyms:

• 1-Naphthalenol, 5-methoxy-2-methyl-

5-Methoxy-2-methyl-Alpha-naphthol-d3

Controlled Product

CAS: 79795-25-8

Applications 5-Methoxy-2-methyl-α-naphthol-d3 is an intermediate in the synthesis of Plumbagin-d3 (P627002). Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Formula: C₁₂H₉D₃O₂

Color and Shape: Neat

Molecular weight: 191.24

Ref: TR-M263652