CAS 79836-45-6

(1R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine

Description:

The chemical substance known as (1R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, with the CAS number 79836-45-6, is a member of the class of compounds known as amines, specifically a substituted tetrahydronaphthalene derivative. This compound features a naphthalene core structure that is partially saturated, which contributes to its unique physical and chemical properties. The presence of a dichlorophenyl group introduces significant steric and electronic effects, influencing its reactivity and potential biological activity. The specific stereochemistry indicated by the (1R,4S) configuration suggests that the compound may exhibit chiral properties, which can affect its interaction with biological targets. Such compounds are often investigated for their potential pharmacological applications, including their roles as neurotransmitter modulators. The molecular structure and substituents can also affect solubility, melting point, and stability, which are critical for its application in various fields, including medicinal chemistry and drug development.

Formula: C₁₇H₁₇Cl₂N

InChI: InChI=1/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17+/m0/s1

Synonyms:

• 1-naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1R,4S)-

rac-trans-Sertraline

Controlled Product

CAS: 79836-45-6

Impurity Sertraline EP Impurity A
Applications rac-trans-Sertraline (Sertraline EP Impurity A) is used for the treatment of menopause and mood, anxiety, and cognitive disorders. They block uptake of dopamine and norepinephrine.
References Welch, W.M., et al.: J. Med. Chem., 27, 1508 (1984).

Formula: C₁₇H₁₇Cl₂N

Color and Shape: Neat

Molecular weight: 306.23

Ref: TR-S279980