CAS 79944-56-2

Idazoxan hydrochloride

Description:

Idazoxan hydrochloride is a chemical compound primarily recognized for its role as an alpha-2 adrenergic antagonist. It is often utilized in pharmacological research to study the effects of modulating adrenergic receptors, particularly in the context of neuropharmacology. The compound exhibits a high affinity for alpha-2 adrenergic receptors, which are involved in various physiological processes, including the regulation of neurotransmitter release. Idazoxan hydrochloride is typically presented as a white to off-white crystalline powder, soluble in water and other polar solvents. Its chemical structure includes a substituted imidazoline ring, contributing to its receptor-binding properties. In addition to its research applications, idazoxan has been investigated for potential therapeutic effects in conditions such as hypertension and anxiety disorders. However, its clinical use is limited, and it is primarily employed in experimental settings. As with any pharmacological agent, safety and efficacy must be thoroughly evaluated in controlled studies before any potential therapeutic applications can be considered.

Formula: C₁₁H₁₂N₂O₂·ClH

InChI: InChI=1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H

InChI key: InChIKey=MYUBYOVCLMEAOH-UHFFFAOYSA-N

SMILES: C1(OC=2C(OC1)=CC=CC2)C=3NCCN3.Cl

Synonyms:

• (±)-Idazoxan monohydrochloride
• 1,4-Benzodioxin, 1H-imidazole deriv.
• 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, hydrochloride (1:1)
• 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride
• 2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
• 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride (1:1)
• Idazoxan hydrochloride
• Rx 781094A
• Rx-781094

Idazoxan (hydrochloride)

CAS: 79944-56-2

Formula: C₁₁H₁₃ClN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 240.6861

Ref: IN-DA008KUC

Idazoxan hydrochloride

CAS: 79944-56-2

Idazoxan hydrochloride

Purity: ≥98%

Molecular weight: 240.69g/mol

Ref: 54-BUP10078

Idazoxan HCl

CAS: 79944-56-2

Formula: C₁₁H₁₂N₂O₂·HCl

Molecular weight: 204.23 36.46

Ref: 4Z-I-146001

Idazoxan hydrochloride

CAS: 79944-56-2

Formula: C₁₁H₁₂N₂O₂·HCl

Molecular weight: 240.69

Ref: 7W-GP6150

Idazoxan hydrochloride

CAS: 79944-56-2

Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity.

Formula: C₁₁H₁₂N₂O₂·HCl

Purity: 99.42% - 99.84%

Color and Shape: Solid

Molecular weight: 240.69

Ref: TM-T0115

Idazoxan Hydrochloride

Controlled Product

CAS: 79944-56-2

Stability Hygroscopic
Applications An α-adrenoceptor antagonist; in rat brain Idazoxan is a pure antagonist and it has a selectivity for α2- over α1-receptors markedly superior to Piperoxane, Yohimbine, or Rauwolscine. Antiparkinsonian.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fliri, A., et al.: Med. Chem., 48, 6918 (2005), Yildirim, M., et al.: Nat. Biotechnol., 25, 1119 (2007),

Formula: C₁₁H₁₃ClN₂O₂

Color and Shape: Neat

Molecular weight: 240.69

Ref: TR-I506800

Idazoxan hydrochloride

CAS: 79944-56-2

selective α2 adrenergic receptor antagonist

Formula: C₁₁H₁₃ClN₂O₂

Purity: Min. 95%

Molecular weight: 240.69 g/mol

Ref: 3D-FI24536