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CAS 79952-42-4

:

Monacolin J

Description:
Monacolin J, with the CAS number 79952-42-4, is a naturally occurring compound primarily derived from the fermentation of rice by the mold Monascus purpureus, commonly known as red yeast rice. It belongs to a class of compounds known as statins, which are known for their ability to inhibit HMG-CoA reductase, an enzyme crucial in cholesterol biosynthesis. This inhibition leads to a reduction in cholesterol levels in the bloodstream, making Monacolin J of interest for its potential cardiovascular benefits. The compound is characterized by its specific chemical structure, which includes a polyketide backbone and various functional groups that contribute to its biological activity. Monacolin J is often studied for its role in dietary supplements aimed at managing cholesterol levels, although its efficacy and safety profile can vary among individuals. As with other statins, it may have side effects and interactions with other medications, necessitating careful consideration in its use.
Formula:C19H28O4
InChI:InChI=1S/C19H28O4/c1-11-7-13-4-3-12(2)16(19(13)17(21)8-11)6-5-15-9-14(20)10-18(22)23-15/h3-4,7,11-12,14-17,19-21H,5-6,8-10H2,1-2H3/t11-,12-,14+,15+,16-,17-,19-/m0/s1
InChI key:InChIKey=ZDFOBOYQVYMVCW-IRUSZSJRSA-N
SMILES:C(C[C@@H]1C[C@@H](O)CC(=O)O1)[C@@H]2[C@@]3(C(C=C[C@@H]2C)=C[C@H](C)C[C@@H]3O)[H]
Synonyms:
  • (4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one
  • 2H-Pyran-2-one, 6-(2-(1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl)ethyl)tetrahydro-4-hydroxy-
  • 2H-Pyran-2-one, 6-[2-(1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl)ethyl]tetrahydro-4-hydroxy-, [1S-[1α(4S*,6S*),2α,6β,8β,8aα]]-
  • 2H-Pyran-2-one, 6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-, (4R,6R)-
  • Antibiotic MB 530A
  • Lovastatin diol lactone
  • Monacolin J
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90
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100
Found 8 products.