CAS 80-49-9
:Homatropine methobromide
Description:
Homatropine methobromide is a synthetic anticholinergic agent primarily used in ophthalmology to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle). It is a quaternary ammonium compound, which means it carries a positive charge, enhancing its solubility in water and limiting its ability to cross the blood-brain barrier. This characteristic reduces central nervous system side effects compared to other anticholinergics. The substance is typically administered as eye drops and is known for its relatively rapid onset of action and moderate duration of effect. In addition to its ophthalmic applications, it may also be used in other medical contexts where anticholinergic effects are desired. Common side effects can include dry mouth, blurred vision, and increased intraocular pressure. Due to its specific pharmacological profile, homatropine methobromide is a valuable tool in both diagnostic and therapeutic settings in eye care.
Formula:C17H24BrNO3
InChI:InChI=1/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3/t12-,13+,14+,15?
InChI key:InChIKey=FUFVKLQESJNNAN-RIMUKSHENA-M
SMILES:C[N+]1(C)[C@]2(C[C@H](OC(C(O)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].[Br-]
Synonyms:- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
- 1αH,5αH-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
- 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-
- 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, endo-
- 8-Methylhomatropinium bromide
- Arkitropin
- Camatropine
- Esopin
- Helbatropin
- Homapin
- Homatrocel
- Homatromide
- Homatropil
- Homatropine Methylbromide
- Homatropine methobromide
- Homatropinmethylbromid
- Homolone
- Malcotran
- Mesopin
- Methatropin
- Methatropine
- Methylbromure d'homatropine
- Methylhomatropine bromide
- Methylhomatropine hydrobromide
- Methylhomatropinium bromide
- Metilbromuro De Homatropina
- Novatrin
- Novatrine
- Novatropin
- Novatropine
- Nsc 34399
- Sed-Tems
- Sethyl
- Tropinium methobromide mandelate
- 3-{[hydroxy(phenyl)acetyl]oxy}-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
- N-methylhomatropinium bromide
- dl-homatropine methyl bromide
- 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, (3-endo)-
- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate - bromomethane (1:1)
- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate
- Homatropine methyl bromide
- dl-methylbromide
- methylhomatropine
- 3-alpha-hydroxy-8-methyl-1-alpha-h,5-alpha-h-tropaniumbromidemandelate
- 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-8-azoniabicyclo(3.2.1)octanbro
- endo-mid
- 8-methyl-homatropiniubromide
- See more synonyms
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Found 13 products.
Homatropine Methyl Bromide
CAS:Formula:C17H24BrNO3Purity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:370.29HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS
CAS:<p>HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS</p>Formula:C16H21NO3Color and Shape:PowderMolecular weight:275.3428HOMATROPINE METHYLBROMIDE CRS
CAS:<p>HOMATROPINE METHYLBROMIDE CRS</p>Formula:C16H21NO3Color and Shape:PowderMolecular weight:275.3428Homatropine Methylbromide
CAS:Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoiFormula:C17H24BrNO3Color and Shape:White Colorless PowderMolecular weight:370.28Methylhomatropine (bromide)
CAS:Formula:C17H24BrNO3Purity:98%Color and Shape:SolidMolecular weight:370.2814Homatropine Methylbromide
CAS:<p>Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.</p>Formula:C17H24BrNO3Purity:98.97%Color and Shape:SolidMolecular weight:370.29Homatropine Methylbromide
CAS:Controlled ProductFormula:C17H24NO3·BrColor and Shape:NeatMolecular weight:370.28Homatropine methylbromide
CAS:Controlled ProductFormula:C17H24NO3·BrColor and Shape:NeatMolecular weight:370.28Homatropine methyl bromide
CAS:<p>Homatropine methyl bromide is a drug that belongs to the class of anticholinergic drugs. It is used as a pharmaceutical preparation and is used in the treatment of glaucoma, diagnosis of myasthenia gravis, and as an antidote for organophosphate poisoning. Homatropine methyl bromide can be used to control diastolic pressure. This drug binds to acetylcholine receptors and increases the time needed for hydrochloric acid to break down propranolol hydrochloride. The binding constants for this drug are high, which means it has a strong affinity for acetylcholine receptors. Homatropine methyl bromide is chemically stable and does not react with fatty acids or other chemicals.</p>Formula:C17H24NO3·BrPurity:Min. 95%Molecular weight:370.28 g/molHomatropine Methylbromide
CAS:Controlled Product<p>Applications Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.<br>References Schroeder, F., et al.: Biochemistry, 34, 11919 (1995); Krungkrai, J., et al.: Bioorg. Med. Chem., 15, 483 (2005); Zeng, B., et al.: Microbiology, 152, 2355 (2006); Hongmanee, P., et al.: Antimicrob. Agents Chemother., 51, 1105 (2007);<br></p>Formula:C17H24NO3·BrColor and Shape:White To Off-WhiteMolecular weight:370.28
