CAS 80-75-1

11α-Hydroxyprogesterone

Description:

11α-Hydroxyprogesterone, also known as 11α-hydroxyprogesterone or 11α-OHP, is a steroid hormone that is a derivative of progesterone. It is characterized by the presence of a hydroxyl group at the 11α position of the steroid nucleus, which influences its biological activity and receptor interactions. This compound is typically a white to off-white crystalline powder and is soluble in organic solvents like ethanol and methanol but has limited solubility in water. 11α-Hydroxyprogesterone plays a significant role in various physiological processes, including the regulation of the menstrual cycle and pregnancy. It is also involved in the synthesis of other steroid hormones. In clinical settings, it may be used in hormone replacement therapy or as part of certain diagnostic tests for adrenal function. Its CAS number, 80-75-1, is a unique identifier that facilitates the identification and study of this compound in scientific literature and regulatory contexts. As with all steroid hormones, its use and administration should be carefully monitored due to potential side effects and interactions.

Formula: C₂₁H₃₀O₃

InChI: InChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18+,19+,20-,21+/m0/s1

InChI key: InChIKey=BFZHCUBIASXHPK-QJSKAATBSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@H]3O)[C@@H](C(C)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (11Alpha)-11-Hydroxypregn-4-Ene-3,20-Dione
• (11Alpha,17Xi)-11-Hydroxypregn-4-Ene-3,20-Dione
• (11α)-11-Hydroxypregn-4-ene-3,20-dione
• 11-Alpha-Hydroxypregn-4-Ene-3,20-Dione
• 11-Hydroxyprogesterone
• 11-alpha-Hydroxyprogesterone
• 11A-hydroxyprogesterone
• 11alpha-Hydroxy-4-pregnene-3,20-dione
• 11α-Hydroxypregn-4-ene-3,20-dione
• 4-Pregnene-11α-ol-3,20-dione
• Dg 322B
• NSC 3350
• Pregn-4-en-11α-ol-3,20-dione
• Pregn-4-ene-3,20-dione, 11-hydroxy-, (11α)-
• Pregn-4-ene-3,20-dione, 11α-hydroxy-
• Progesterone, 11α-hydroxy-

11α-Hydroxyprogesterone

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 330.4611

Ref: IN-DA0058BJ

11-α-Hydroxyprogesterone

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Purity: ≥ 95.0% (dried basis)

Color and Shape: White powder

Molecular weight: 330.46

Ref: 7W-GK8220

11-alfa-Hydroxy Progesterone

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Color and Shape: White To Off-White Solid

Molecular weight: 330.47

Ref: 4Z-P-3251

11α-Hydroxyprogesterone

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Purity: >95.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 330.47

Ref: 3B-H0498

11α-Hydroxyprogesterone

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Color and Shape: Neat

Molecular weight: 330.46

Ref: 04-C14240950

11α-Hydroxyprogesterone

Controlled Product

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Color and Shape: Neat

Molecular weight: 330.46

Ref: 86-MM0222.08

11α-Hydroxy Progesterone

Controlled Product

CAS: 80-75-1

Applications Progesterone (P755900) metabolite.
References Christy H., et al.: J. Steroid Biochem., Mol., Biol., 116, 171 (2009), Peristera, O., et al.: Toxicol., Lett., 189, 219 (2009), Mori, T., et al.: Toxicol., Lett., 186, 123 (2009),

Formula: C₂₁H₃₀O₃

Color and Shape: Off-White

Molecular weight: 330.46

Ref: TR-H952335

11α-Hydroxy Progesterone

CAS: 80-75-1

Formula: C₂₁H₃₀O₃

Molecular weight: 330.47

Ref: ST-EA-CP-P133072

11a-Hydroxy progesterone

Controlled Product

CAS: 80-75-1

11α-Hydroxy progesterone is a steroid metabolite, which is derived from progesterone via enzymatic hydroxylation. This compound is produced synthetically or through microbial transformation. It functions primarily by serving as an intermediate in the biosynthesis of various steroid hormones, engaging in pathways that modify and regulate hormone activity.

Formula: C₂₁H₃₀O₃

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 330.47 g/mol

Ref: 3D-FH24102

11α-Hydroxyprogesterone

CAS: 80-75-1

11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an effective dose (ED)50 of 10 nM.

Formula: C₂₁H₃₀O₃

Color and Shape: Solid

Molecular weight: 330.468

Ref: TM-T84842