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CAS 8001-27-2

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Hirudin

Description:
Hirudin is a naturally occurring peptide that serves as a potent anticoagulant, primarily derived from the saliva of leeches, particularly the species Hirudo medicinalis. It functions by specifically inhibiting thrombin, an enzyme crucial for blood coagulation, thereby preventing the conversion of fibrinogen to fibrin and ultimately reducing blood clot formation. Hirudin is composed of a sequence of amino acids, typically containing around 65 residues, and exhibits a high degree of specificity and affinity for thrombin. Its structure includes several disulfide bonds that contribute to its stability and biological activity. Due to its anticoagulant properties, hirudin has been studied for therapeutic applications in conditions requiring anticoagulation, such as deep vein thrombosis and pulmonary embolism. Additionally, it has been utilized in research settings to better understand coagulation processes and the mechanisms of thrombin inhibition. As a biopharmaceutical, hirudin is subject to rigorous quality control and characterization to ensure its efficacy and safety in clinical use.
Formula:C287H440N80O110S6
Synonyms:
  • Exhirud
  • Exhirudine
  • Hirudex
  • Hirudina
  • Sangsue
  • Hirudin
  • (63-tyrosine)hirudin (hv1),leech,rec. F. yeast
  • [Tyr63]Hirudin (HV1), leech recombinant, from yeast
  • Hirudin, Hirudo medicinalis, Recombinant, Saccharomyces Cere
  • Hirudin recombinant from yeast
  • See more synonyms
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Found 2 products.
  • Recombinant Hirudin
    Apollo Scientific
    + Info

    Recombinant Hirudin

    CAS:
    <p>Recombinant Hirudin</p>
    Color and Shape:White Powder

    Ref: 54-BITP1576

    1mg
    3,175.00€
    2µg
    186.00€
    10µg
    263.00€
  • Hirudin from leeches
    Biosynth
    + Info

    Hirudin from leeches

    CAS:
    <p>Hirudin is a potent anticoagulant protein, which is a naturally occurring compound sourced from the salivary glands of medicinal leeches, specifically *Hirudo medicinalis*. It functions by directly inhibiting thrombin, a key enzyme in the blood coagulation process, thereby preventing fibrin formation and subsequent clot development. Hirudin achieves its effects by binding to both the active site and the exosite of thrombin, effectively neutralizing its coagulative activity.</p>
    Formula:C287H440N80O110S6
    Purity:Min. 95%
    Molecular weight:6 g/mol

    Ref: 3D-XH173313

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