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CAS 80054-80-4

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1-chloro-4-(2,2,2-trifluoroethoxy)benzene

Description:
1-Chloro-4-(2,2,2-trifluoroethoxy)benzene is an organic compound characterized by its aromatic structure, featuring a chlorine atom and a trifluoroethoxy group attached to a benzene ring. The presence of the chlorine atom contributes to its reactivity, making it a potential intermediate in various chemical syntheses. The trifluoroethoxy group, which consists of a trifluoroethyl moiety linked to an ether oxygen, imparts unique properties such as increased lipophilicity and thermal stability. This compound is typically colorless to pale yellow and may exhibit a distinct odor. It is soluble in organic solvents but has limited solubility in water due to its hydrophobic characteristics. The trifluoromethyl groups enhance its electron-withdrawing properties, which can influence its reactivity in electrophilic aromatic substitution reactions. Safety considerations should be taken into account, as halogenated compounds can pose environmental and health risks. Overall, 1-chloro-4-(2,2,2-trifluoroethoxy)benzene is of interest in both industrial applications and research settings, particularly in the development of pharmaceuticals and agrochemicals.
Formula:C8H6ClF3O
InChI:InChI=1/C8H6ClF3O/c9-6-1-3-7(4-2-6)13-5-8(10,11)12/h1-4H,5H2
SMILES:c1cc(ccc1Cl)OCC(F)(F)F
Synonyms:
  • 4-Chlorophenyl 2,2,2-trifluoroethyl ether
  • Benzene, 1-Chloro-4-(2,2,2-Trifluoroethoxy)-
  • 1-Chloro-4-(2,2,2-trifluoroethoxy)benzene
  • 4-(2,2,2-Trifluoroethoxy)chlorobenzene
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