CAS 801-52-5: Porfiromycin

Description:Porfiromycin is an antibiotic compound that belongs to the class of macrolide antibiotics. It is derived from the fermentation of certain strains of Streptomyces bacteria. The chemical structure of porfiromycin features a large lactone ring, which is characteristic of macrolides, and it possesses various functional groups that contribute to its biological activity. This compound exhibits antibacterial properties, particularly against Gram-positive bacteria, and has been studied for its potential use in treating various infections. Porfiromycin's mechanism of action involves inhibiting bacterial protein synthesis, which ultimately leads to the cessation of bacterial growth. Additionally, it has shown some antitumor activity, making it of interest in cancer research. The substance is typically administered in a clinical setting, and its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are crucial for determining its therapeutic efficacy and safety profile. As with many antibiotics, the emergence of resistance is a concern, necessitating ongoing research into its effectiveness and potential alternatives.

Formula:C₁₆H₂₀N₄O₅

InChI:InChI=1S/C16H20N4O5/c1-6-10(17)13(22)9-7(5-25-15(18)23)16(24-3)14-8(19(14)2)4-20(16)11(9)12(6)21/h7-8,14H,4-5,17H2,1-3H3,(H2,18,23)/t7-,8+,14+,16-,19?/m1/s1

InChI key:InChIKey=HRHKSTOGXBBQCB-VFWICMBZSA-N

SMILES:O=C(OCC1C=2C(=O)C(N)=C(C(=O)C2N3CC4N(C)C4C31OC)C)N

Synonyms:
(1aS,8S,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethylazirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione
(6-Amino-8A-Methoxy-1,5-Dimethyl-4,7-Dioxo-1,1A,2,4,7,8,8A,8B-Octahydroazireno[2',3':3,4]Pyrrolo[1,2-A]Indol-8-Yl)Methyl Carbamate
6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-1,5-dimethylazirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione carbamate (ester)
Ai3-50825
Azirino(2',3':3,4)pyrrolo(1,2-a)-indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-1,5-dimethyl-, carbamate (ester) (8CI)
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-1,5-dimethyl-, carbamate (ester)
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-1,5-dimethyl-,(1aR-(1aalpha,8beta,8aalpha,8balpha))- (9CI)
Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-1,5-dimethyl-, carbamate (ester)
Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-, (1aS,8S,8aR,8bS)-
See more synonyms
Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-, [1aS-(1aα,8β,8aα,8bα)]-
Ent-50825
Methyl mitomycin C
Methylmitomycin
Mitomycin C, N-methyl-
N-Methylmitomycin C
Nci 56410
Nsc 56410
Porfiromicina
Porfiromicina [INN-Spanish]
Porfiromycin [USAN:INN:BAN]
Porfiromycine
Porfiromycine [INN-French]
Porfiromycinum
Porfiromycinum [INN-Latin]
Porphyromycin
Regamycin
U-14743
Unii-H1Wk901Oa6
[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
Porfiromycin

Found 3 products.

Product data	Purity	Price range	Estimated delivery
Porfiromycin REF: TR-P689450CAS: 801-52-5	- - -	418.00 €~2,751.00 €	Tue 13 May 25
Porfiromycin REF: 3D-AP27106CAS: 801-52-5	Min. 95 Area-%	531.00 €~3,691.00 €	Thu 12 Jun 25
Porfiromycin REF: TM-T68675CAS: 801-52-5	- - -	1,444.00 €~2,375.00 €	Fri 20 Jun 25