Tyrocidines are a group of cyclic decapeptides produced by the bacterium Bacillus thuringiensis. They are known for their antimicrobial properties, particularly against Gram-positive bacteria and some fungi. Tyrocidines exhibit a unique structure characterized by a cyclic arrangement of amino acids, which contributes to their ability to disrupt microbial cell membranes. This disruption leads to increased permeability, ultimately resulting in cell lysis and death. Tyrocidines are also noted for their ability to form complexes with lipids, enhancing their antimicrobial efficacy. In addition to their antibacterial activity, they have been studied for potential applications in agriculture and medicine, particularly as natural preservatives or therapeutic agents. However, their use is limited by potential toxicity to human cells and the environment. Overall, tyrocidines represent an important class of natural antimicrobial agents with significant research interest in their mechanisms of action and potential applications.

Tyrocidines

8011-61-8: Tyrocidines are a group of cyclic decapeptides produced by the bacterium Bacillus thuringiensis. They are known for their antimicrobial properties, particularly against Gram-positive bacteria and some fungi. Tyrocidines exhibit a unique structure characterized by a cyclic arrangement of amino acids, which contributes to their ability to disrupt microbial cell membranes. This disruption leads to increased permeability, ultimately resulting in cell lysis and death. Tyrocidines are also noted for their ability to form complexes with lipids, enhancing their antimicrobial efficacy. In addition to their antibacterial activity, they have been studied for potential applications in agriculture and medicine, particularly as natural preservatives or therapeutic agents. However, their use is limited by potential toxicity to human cells and the environment. Overall, tyrocidines represent an important class of natural antimicrobial agents with significant research interest in their mechanisms of action and potential applications.

<p>Tyrocidine, a cyclic decapeptide from B. brevis, fights Gram-positive/negative bacteria by inhibiting RNA synthesis by binding DNA.</p>

CAS 8011-61-8

Tyrocidines

Tyrocidine Complex

Ref: TM-T36298