CAS 80118-77-0

4'-O-demethyldianemycin

Description:

4'-O-Demethyldianemycin, with the CAS number 80118-77-0, is a chemical compound that belongs to the class of macrolide antibiotics. It is derived from the natural product dianemycin, which is known for its antibacterial properties. The structure of 4'-O-demethyldianemycin features a macrolide ring, which is characteristic of many antibiotics in this class, providing it with a unique mechanism of action that typically involves inhibition of bacterial protein synthesis. This compound exhibits activity against a range of Gram-positive bacteria, making it of interest in the field of medicinal chemistry and pharmacology. Its solubility, stability, and bioavailability are important factors that influence its therapeutic potential. Additionally, as with many antibiotics, the development of resistance is a significant concern, necessitating ongoing research into its efficacy and the mechanisms by which bacteria may evade its effects. Overall, 4'-O-demethyldianemycin represents a valuable compound in the search for effective antibacterial agents.

Formula: C₄₆H₇₇NaO₁₄

InChI: InChI=1/C46H76O14.Na/c1-11-12-32(39(50)25(2)17-27(4)41(51)52)21-42(9)24-54-44(22-36(42)49)16-15-43(10,60-44)37-20-34(56-38-14-13-33(48)31(8)55-38)30(7)46(58-37)29(6)19-35(57-46)40-26(3)18-28(5)45(53,23-47)59-40;/h12,25-31,33-38,40,47-49,53H,11,13-24H2,1-10H3,(H,51,52);/q;+1/p-1/b32-12+;/t25?,26-,27?,28+,29+,30+,31+,33-,34-,35+,36-,37+,38+,40?,42-,43-,44?,45-,46?;/m0./s1

Synonyms:

• 4'-O-demethyldianemycin
• 4'-O-Demethyldianemycin sodium salt
• Antibiotic TM-531B
• TM-531B

4'-O-Demethyldianemycin

CAS: 80118-77-0

4'-O-Demethyldianemycin (TM-531B) is a polyether antibiotic produced by Streptomyces hygroscopicus TM-531, demonstrating activity against Gram-positive bacteria.

Formula: C₄₆H₇₅NaO₁₄

Color and Shape: Solid

Molecular weight: 875.07

Ref: TM-TN10968