CAS 801283-95-4

Faldaprevir

Description:

Faldaprevir is an antiviral medication primarily used in the treatment of hepatitis C virus (HCV) infections. It belongs to the class of drugs known as protease inhibitors, which work by inhibiting the viral NS3/4A protease, an enzyme crucial for the replication of the virus. Faldaprevir is characterized by its ability to target specific viral proteins, thereby disrupting the life cycle of HCV and reducing viral load in infected patients. The compound has a relatively complex chemical structure, which contributes to its specificity and efficacy against HCV. It is typically administered in combination with other antiviral agents to enhance therapeutic outcomes and reduce the risk of resistance. Faldaprevir has been studied for its pharmacokinetics, showing a favorable absorption profile, and is metabolized primarily in the liver. As with many antiviral medications, potential side effects may include fatigue, nausea, and liver enzyme elevations, necessitating monitoring during treatment. Overall, Faldaprevir represents a significant advancement in the management of hepatitis C, contributing to improved cure rates when used in combination therapies.

Formula: C₄₀H₄₉BrN₆O₉S

InChI: InChI=1S/C40H49BrN6O9S/c1-8-21-17-40(21,36(51)52)46-34(49)27-15-23(18-47(27)35(50)32(39(4,5)6)44-38(53)56-22-11-9-10-12-22)55-29-16-25(26-19-57-37(43-26)45-33(48)20(2)3)42-31-24(29)13-14-28(54-7)30(31)41/h8,13-14,16,19-23,27,32H,1,9-12,15,17-18H2,2-7H3,(H,44,53)(H,46,49)(H,51,52)(H,43,45,48)/t21-,23-,27+,32-,40-/m1/s1

InChI key: InChIKey=LLGDPTDZOVKFDU-XUHJSTDZSA-N

SMILES: N(C(=O)[C@H]1N(C([C@@H](NC(OC2CCCC2)=O)C(C)(C)C)=O)C[C@H](OC=3C4=C(N=C(C3)C=5N=C(NC(C(C)C)=O)SC5)C(Br)=C(OC)C=C4)C1)[C@@]6(C(O)=O)[C@H](C=C)C6

Synonyms:

• BI 201335
• Faldaprevir
• BI 1335
• Cyclopropanecarboxylic acid, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-bromo-7-methoxy-2-[2-[(2-methyl-1-oxopropyl)amino]-4-thiazolyl]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethenyl-, (1R,2S)-

Faldaprevir

CAS: 801283-95-4

Formula: C₄₀H₄₉BrN₆O₉S

Color and Shape: White To Off-White Solid

Molecular weight: 869.84

Ref: 4Z-F-088001

Faldaprevir

CAS: 801283-95-4

Faldaprevir

Purity: ≥98%

Molecular weight: 869.82g/mol

Ref: 54-BUP21249

Faldaprevir-d7

CAS: 801283-95-4

Formula: C₄₀H₄₂BrN₆O₉SD₇

Molecular weight: 876.88

Ref: 4Z-F-088004

Faldaprevir-d6

CAS: 801283-95-4

Formula: C₄₀H₄₃D₆BrN₆O₉S

Color and Shape: Pale Yellow Solid

Molecular weight: 875.87

Ref: 4Z-F-088003

Faldaprevir

CAS: 801283-95-4

Hepatitis C virus protease inhibitor

Formula: C₄₀H₄₉BrN₆O₉S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 869.82 g/mol

Ref: 3D-FF72051

Faldaprevir

CAS: 801283-95-4

Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.

Formula: C₄₀H₄₉BrN₆O₉S

Purity: 99.04% - 99.19%

Color and Shape: Solid

Molecular weight: 869.82

Ref: TM-T19685