CAS 80146-85-6

Glutaminylpeptide γ-glutamyltransferase

Description:

Glutaminylpeptide γ-glutamyltransferase, identified by the CAS number 80146-85-6, is an enzyme that plays a crucial role in the metabolism of glutamine and related compounds. This enzyme is involved in the transfer of γ-glutamyl groups from glutathione or other γ-glutamyl compounds to amino acids or peptides, facilitating the synthesis of various bioactive molecules. It is typically found in various tissues, including the liver and kidneys, and is important for maintaining cellular homeostasis and detoxification processes. The enzyme exhibits specificity for certain substrates and is influenced by factors such as pH and temperature, which can affect its activity. Additionally, it may have implications in various physiological and pathological processes, including amino acid transport and the modulation of oxidative stress. Understanding the characteristics and functions of this enzyme can provide insights into its potential therapeutic applications and its role in metabolic disorders.

Formula: Unspecified

Synonyms:

• E.C. 2.3.2.13
• Glutaminylpeptide γ-glutamyltransferase
• Glutamyltransferase, glutaminylpeptide γ-
• Transglutaminase
• Polyamine transglutaminase

Transglutaminase

CAS: 80146-85-6

Transglutaminase (TG) induces intermolecular cross-linking of proteins and is involved in coagulation, antimicrobial immune responses and photosynthesis.

Color and Shape: Solid

Ref: TM-T78362

Transglutaminase (From Streptoverticillium mobaraense)

CAS: 80146-85-6

Transglutaminase (From Streptoverticillium mobaraense)

Ref: 54-BI12286

Transglutaminase from guinea pig liver

CAS: 80146-85-6

Transglutaminase (2.3.2.13) is an enzyme that catalyzes formation of isopeptide bonds between the γ-carboxamide groups ( -(C=O)NH2 ) of glutamine side chains and amino groups. The donor of the amino group is usually (but not always) an ε-amino group ( -NH2 ) of lysine residue. The reaction also releases ammonia: Gln-(C=O)NH2 + NH2-Lys → Gln-(C=O)NH-Lys + NH3One unit of transglutaminase will catalyze the formation of 1.0 μmole transglutamination product per min at pH 6.0 and 37 °C.

Purity: Min. 95%

Ref: 3D-FDA14685

Transglutaminase from streptoverticillium mobaraense

CAS: 80146-85-6

selectively deamidates gluten peptides, which results in strongly enhanced T cell-stimulatory activity.  It has also been used in a study to improve quantifiable assays to fully characterize the role of transglutaminase in diseases such as Huntington′s disease and Alzheimer′s disease.

Color and Shape: Powder

Ref: 3D-ET183066