CAS 80194-69-0

5-(Trifluoromethyl)pyridine-2-carboxylic acid

Description:

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an aromatic carboxylic acid characterized by the presence of a pyridine ring substituted with a trifluoromethyl group and a carboxylic acid functional group. This compound typically exhibits a pale yellow to white crystalline appearance. The trifluoromethyl group contributes to its unique electronic properties, enhancing its lipophilicity and potentially influencing its reactivity and interactions in various chemical environments. The carboxylic acid group provides acidic properties, allowing it to participate in hydrogen bonding and act as a proton donor. This compound is often utilized in organic synthesis and medicinal chemistry, serving as an intermediate in the production of pharmaceuticals and agrochemicals. Its distinct fluorinated structure may also impart specific biological activities, making it of interest in drug development. Additionally, the compound's stability and solubility characteristics can vary based on the solvent and conditions, which are important considerations in its practical applications.

Formula: C₇H₄F₃NO₂

InChI: InChI=1/C7H4F3NO2/c8-7(9,10)4-1-2-5(6(12)13)11-3-4/h1-3H,(H,12,13)

InChI key: InChIKey=NJHGVAYLDHROPT-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C=CC(C(O)=O)=NC1

Synonyms:

• 2-Pyridinecarboxylic acid, 5-(trifluoromethyl)-
• 5-(Trifluoromethyl)-2-pyridinecarboxylic acid
• 5-(Trifluoromethyl)picolinic acid
• 5-Trifluoromethylpicolinic acid
• 5-(Trifluoromethyl)pyridine-2-carboxylic acid
• 5-Trifluoromethyl-2-Pyridineca
• 5-(Trifluoromethyl)pyridine-2-carboxylic acid 97%
• 5-(Trifluoromethyl)pyridine-2-carboxylicacid97%

5-(Trifluoromethyl)-2-pyridinecarboxylic Acid

CAS: 80194-69-0

Formula: C₇H₄F₃NO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 191.11

Ref: 3B-T2975

5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95%

CAS: 80194-69-0

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of -secretase (BACE) inhibitors. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The

Formula: C₇H₄F₃NO₂

Purity: 95%

Molecular weight: 191.11

Ref: 02-H64937

5-(Trifluoromethyl)pyridine-2-carboxylic acid

CAS: 80194-69-0

Formula: C₇H₄F₃NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.1074

Ref: IN-DA008NBA

5-(Trifluoromethyl)pyridine-2-carboxylic acid

CAS: 80194-69-0

5-(Trifluoromethyl)pyridine-2-carboxylic acid

Formula: C₇H₄F₃NO₂

Purity: 97%

Color and Shape: white fine powder

Molecular weight: 191.11g/mol

Ref: 54-PC9132

5-(Trifluoromethyl)-2-pyridinecarboxylic acid

CAS: 80194-69-0

Formula: C₇H₄F₃NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.109

Ref: 10-F037264

5-(Trifluoromethyl)picolinic Acid

Controlled Product

CAS: 80194-69-0

Applications 5-(Trifluoromethyl)picolinic Acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.
References Tresadern, G., et al.: Bioorg. Med. Chem. Lett., 21, 7255 (2011); Watanabe, T., et al.: Bioorg. Med. Chem., 20, 5839 (2010);

Formula: C₇H₄F₃NO₂

Color and Shape: Neat

Molecular weight: 191.11

Ref: TR-T791430