CAS 80200-09-5

4-(1H-pyrazol-1-ylmethyl)phenol

Description:

4-(1H-pyrazol-1-ylmethyl)phenol, identified by its CAS number 80200-09-5, is an organic compound characterized by the presence of a phenolic group and a pyrazole moiety. This compound typically exhibits a white to off-white crystalline appearance and is soluble in organic solvents, with limited solubility in water. The structure features a phenol ring substituted with a pyrazolylmethyl group, which can influence its chemical reactivity and biological activity. The presence of the pyrazole ring may impart unique properties, such as potential antioxidant or antimicrobial activities, making it of interest in pharmaceutical and agricultural applications. Additionally, the compound may participate in various chemical reactions, including nucleophilic substitutions and complexation with metal ions. Its stability and reactivity can be influenced by factors such as pH and the presence of other functional groups. Overall, 4-(1H-pyrazol-1-ylmethyl)phenol is a versatile compound with potential applications in medicinal chemistry and materials science.

Formula: C₁₀H₁₀N₂O

InChI: InChI=1/C10H10N2O/c13-10-4-2-9(3-5-10)8-12-7-1-6-11-12/h1-7,13H,8H2

Synonyms:

• phenol, 4-(1H-pyrazol-1-ylmethyl)-

4-[(1H-Pyrazol-1-yl)methyl]phenol

CAS: 80200-09-5

4-[(1H-Pyrazol-1-yl)methyl]phenol (4PMP) is an inhibitor of dopamine beta-hydroxylase that has been studied in assays with dopamine and noradrenaline. It has been shown to activate both noradrenaline and dopamine receptors, and can be used as a tool for the study of blood pressure regulation. 4PMP also increases reactive oxygen species production, which may be due to its ability to react with cyanide ions. The binding of 4PMP to the enzyme is reversible and competitive. The pH profile of 4PMP has also been studied, with a range from 2 to 5.4. Kinetic studies have shown that the reaction rate for 4PMP is best described by a Michaelis-Menten kinetic model, with a Km value of 0.03 mM and Vmax value of 9.3 μM/min for dopamine β-hydroxylase inhibition. There are

Formula: C₁₀H₁₀N₂O

Purity: Min. 95%

Molecular weight: 174.2 g/mol

Ref: 3D-FDA20009