CAS 80210-62-4

Cefpodoxime

Description:

Cefpodoxime is a broad-spectrum cephalosporin antibiotic used primarily to treat bacterial infections. It is classified as a third-generation cephalosporin and is effective against a variety of Gram-positive and Gram-negative bacteria. The chemical structure of cefpodoxime includes a beta-lactam ring, which is essential for its antibacterial activity, and a side chain that enhances its stability against certain beta-lactamases. Cefpodoxime is typically administered orally and is well-absorbed in the gastrointestinal tract, with its bioavailability being influenced by food intake. It is commonly used to treat respiratory tract infections, urinary tract infections, and skin infections. The drug is generally well-tolerated, but potential side effects may include gastrointestinal disturbances, allergic reactions, and alterations in liver function tests. As with other antibiotics, it is crucial to use cefpodoxime judiciously to minimize the risk of developing antibiotic resistance. Its CAS number, 80210-62-4, is a unique identifier that facilitates the identification and regulation of this compound in various chemical databases.

Formula:C₁₅H₁₇N₅O₆S₂

InChI:InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1

InChI key:InChIKey=WYUSVOMTXWRGEK-HBWVYFAYSA-N

SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1COC)[H]

Synonyms:

(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, [6R-[6α,7β(Z)]]-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, (6R,7R)-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, (6R,7R)-
7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefpodoxime acid
Fpodoxime
Orelox
R 3763
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