CAS 80225-53-2

rosmanol

Description:

Rosmanol, with the CAS number 80225-53-2, is a natural compound primarily derived from rosemary (Rosmarinus officinalis) and is classified as a monoterpene. It is known for its characteristic aromatic properties, contributing to the distinctive scent of rosemary. Rosmanol exhibits various biological activities, including antioxidant, antimicrobial, and anti-inflammatory effects, making it of interest in both food preservation and potential therapeutic applications. The compound is typically found in essential oils and has been studied for its potential health benefits, including its role in enhancing cognitive function and its protective effects against oxidative stress. In terms of physical properties, rosmanol is generally a colorless to pale yellow liquid with a pleasant herbal aroma. Its solubility characteristics allow it to be utilized in various formulations, including cosmetics and fragrances. Overall, rosmanol represents a valuable compound in both the culinary and pharmaceutical industries due to its diverse functional properties.

Formula: C₂₀H₂₆O₅

InChI: InChI=1/C20H26O5/c1-9(2)10-8-11-12(15(23)13(10)21)20-7-5-6-19(3,4)17(20)16(14(11)22)25-18(20)24/h8-9,14,16-17,21-23H,5-7H2,1-4H3/t14-,16+,17-,20-/m0/s1

Synonyms:

• (6beta,7alpha)-7,11,12-Trihydroxy-6,20-epoxyabieta-8(14),9(11),12-trien-20-one
• 2H-10,4a-(epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10S,10aS)-
• [4aR-(4aa,9b,10a,10ab)]-1,3,4,9,10,10a-Hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-2H-10,4a-(epoxymethano)phenanthren-12-one

Rosmanol

CAS: 80225-53-2

Formula: C₂₀H₂₆O₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 346.4174

Ref: IN-DA00G2L1

Rosmanol

CAS: 80225-53-2

Rosmanol

Purity: ≥95%

Molecular weight: 346.42g/mol

Ref: 54-BUP03465

Rosmanol

CAS: 80225-53-2

Formula: C₂₁H₂₈O₄

Molecular weight: 344.45

Ref: 7W-GY2973

Rosmanol

CAS: 80225-53-2

Rosmanol has antioxidant activity, it can activate the antioxidant response element, it also has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol exhibits significant cytotoxicity towards the neuroblastoma cells, it potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells.Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways.

Formula: C₂₀H₂₆O₅

Purity: 95%~99%

Molecular weight: 346.423

Ref: BP-BP3643

Rosmanol

CAS: 80225-53-2

Lactone

Formula: C₂₀H₂₆O₅

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 346.42

Ref: 5G-83268

Rosmanol

Controlled Product

CAS: 80225-53-2

Rosmanol is a bioactive phenolic compound that has been isolated from the root bark of the plant Rosmarinus officinalis. It has been shown to have strong antimicrobial activity against bacteria and fungi. Rosmanol has also been shown to inhibit the production of PGE2, a pro-inflammatory lipid mediator. The compound was found to be highly cytotoxic in vitro when tested against human colon cancer cells (HT-29) and mouse melanoma cells (B16). Structural analysis revealed that rosmanol contains caffeic acids, which have been linked with anticancer properties.

Formula: C₂₀H₂₆O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 346.42 g/mol

Ref: 3D-FR167087

Rosmanol

CAS: 80225-53-2

Rosmanol has antioxidant, anti-inflammatory, CNS effects; induces apoptosis in cancer cells; modulates GABAA receptors.

Formula: C₂₀H₂₆O₅

Purity: 98.82% - 99.79%

Color and Shape: Solid

Molecular weight: 346.42

Ref: TM-T7033