CAS 80251-23-6

H-GLU-HIS-GLY-OH

Description:

The chemical substance known as H-GLU-HIS-GLY-OH, with the CAS number 80251-23-6, is a peptide composed of three amino acids: glutamic acid (GLU), histidine (HIS), and glycine (GLY). This peptide is characterized by its specific sequence and the presence of a hydroxyl group (-OH) at the C-terminus, which can influence its solubility and reactivity. Peptides like H-GLU-HIS-GLY-OH are often studied for their biological activities, including potential roles in signaling pathways, enzyme regulation, and as precursors for larger proteins. The presence of histidine may impart unique properties, such as buffering capacity and metal ion binding, while glutamic acid contributes to the overall charge and polarity of the molecule. Glycine, being the simplest amino acid, can provide flexibility to the peptide structure. Overall, the characteristics of this peptide make it of interest in biochemical research, particularly in the fields of pharmacology and molecular biology.

Formula: C₁₃H₁₉N₅O₆

Synonyms:

• EHG
• Reaxys ID: 25775518
• H-GLU-HIS-GLY-OH
• (S)-4-amino-5-(((S)-1-((carboxymethyl)amino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)amino)-5-oxopentanoicacid
• Glycine, L-α-glutamyl-L-histidyl-

H-Glu-His-Gly-OH

CAS: 80251-23-6

H-Glu-His-Gly-OH is a pentagastrin that is used as a biological agent to release stomach acid and pepsin. It is an exogenous, hormonal gastric juice stimulant that is released in response to the presence of food in the stomach. This hormone has been found to stimulate the production of liquids and monomers in the pancreas, which are needed for digestion. H-Glu-His-Gly-OH works by activating membrane receptors on cells lining the stomach, causing them to release hormones that act on other parts of the body. This hormone also has crosslinked properties, meaning it can be used as a sealant or glue for wounds that do not require stitches. The synthetic version of this pentagastrin is made from liquid or solid organic solvents and is soluble in water or oils. This synthetic form typically comes as micronized powder or granules.

Formula: C₁₃H₁₉N₅O₆

Purity: Min. 95%

Molecular weight: 341.32 g/mol

Ref: 3D-FG110444