CAS 80288-49-9

Furafylline

Description:

Furafylline, with the CAS number 80288-49-9, is a chemical compound that belongs to the class of xanthine derivatives. It is primarily recognized for its role as a selective inhibitor of the enzyme xanthine oxidase, which is involved in purine metabolism. This inhibition can lead to decreased production of uric acid, making furafylline of interest in the treatment of conditions such as gout. The compound exhibits anti-inflammatory properties and has been studied for its potential therapeutic applications in various diseases. Furafylline is typically characterized by its molecular structure, which includes a fused ring system that contributes to its biological activity. It is important to note that, like many pharmacological agents, furafylline may have side effects and contraindications, necessitating careful consideration in clinical use. Additionally, its solubility, stability, and reactivity can vary based on environmental conditions, influencing its application in research and medicine.

Formula: C₁₂H₁₂N₄O₃

InChI: InChI=1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14)

InChI key: InChIKey=KGQZGCIVHYLPBH-UHFFFAOYSA-N

SMILES: C(N1C2=C(C(=O)N(C)C1=O)NC(C)=N2)C3=CC=CO3

Synonyms:

• 3-(2-Furanylmethyl)-3,9-dihydro-1,8-dimethyl-1H-purine-2,6-dione
• Furafylline
• 1H-Purine-2,6-dione, 3-(2-furanylmethyl)-3,7-dihydro-1,8-dimethyl-
• 1H-Purine-2,6-dione, 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-

Furafylline

CAS: 80288-49-9

Formula: C₁₂H₁₂N₄O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 260.25

Ref: 3B-F1365

1H-Purine-2,6-dione,3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-

CAS: 80288-49-9

Formula: C₁₂H₁₂N₄O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 260.2487

Ref: IN-DA00541W

3-(2-Furanylmethyl)-3,7-Dihydro-1,8-Dimethyl-1H-Purine-2,6-Dione

CAS: 80288-49-9

3-(2-Furanylmethyl)-3,7-Dihydro-1,8-Dimethyl-1H-Purine-2,6-Dione

Purity: 99%

Molecular weight: 260.25g/mol

Ref: 54-OR1010640

Furafylline

CAS: 80288-49-9

Furafylline

Purity: ≥98%

Molecular weight: 260.25g/mol

Ref: 54-BUP02643

Furafylline

CAS: 80288-49-9

Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM),

Formula: C₁₂H₁₂N₄O₃

Purity: 99.61%

Color and Shape: Solid

Molecular weight: 260.25

Ref: TM-T7410

Furafylline

CAS: 80288-49-9

Formula: C₁₂H₁₂N₄O₃

Molecular weight: 260.25

Ref: 4Z-F-201001

Furafylline

Controlled Product

CAS: 80288-49-9

Applications Furafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine.
References Sesardic, D., et al.: Br. J. Clin. Pharmacol., 29, 651 (1990); Tarrus, E., et al.: Br. J. Clin. Pharmacol., 23, 9 (1987)

Formula: C₁₂H₁₂N₄O₃

Color and Shape: Neat

Molecular weight: 260.25

Ref: TR-F864070

Furafylline

Controlled Product

CAS: 80288-49-9

Furafylline is a drug that is used to treat asthma and chronic obstructive pulmonary disease. Furafylline inhibits cytochrome P450 1A2, which is involved in the metabolism of many drugs. Furafylline also inhibits cytochrome P450 2C9, 3A4, and 2D6. Furafylline has been shown to inhibit the activity of natural compounds such as dinucleotide phosphate and chemical inhibitors such as paracetamol. Furafylline has also been shown to have a matrix effect on human liver microsomes.

Formula: C₁₂H₁₂N₄O₃

Purity: Min. 95%

Molecular weight: 260.25 g/mol

Ref: 3D-FDA28849

Furafylline

CAS: 80288-49-9

Formula: C₁₂H₁₂N₄O₃

Purity: ≥98%

Molecular weight: 260.253

Ref: 10-F546093