CAS 804-30-8

Fursultiamine

Description:

Fursultiamine, also known as thiamine propyl disulfide, is a synthetic derivative of thiamine (vitamin B1) that is primarily used as a dietary supplement and in the treatment of thiamine deficiency. It is characterized by its ability to enhance the bioavailability of thiamine, making it more effective in the body. Fursultiamine is soluble in lipids, which allows for better absorption compared to water-soluble thiamine. The compound is often utilized in formulations aimed at improving neurological function and energy metabolism, as thiamine plays a crucial role in carbohydrate metabolism and nerve function. Its chemical structure includes a disulfide bond, which contributes to its unique properties and efficacy. Fursultiamine is generally considered safe when used as directed, but like any supplement, it may have potential side effects or interactions with other medications. As with any therapeutic agent, it is important to consult healthcare professionals before use, especially in individuals with underlying health conditions or those taking other medications.

Formula: C₁₇H₂₆N₄O₃S₂

InChI: InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)

InChI key: InChIKey=JTLXCMOFVBXEKD-UHFFFAOYSA-N

SMILES: C(N(C(=C(SSCC1CCCO1)CCO)C)C=O)C=2C(N)=NC(C)=NC2

Synonyms:

• Adventan
• Alinamin F
• Diteftin
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-
• Fursultiamin
• Fursultiamine
• Judolor
• Linamin
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]formamide
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{(1Z)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{5-hydroxy-3-[(tetrahydrofuran-2-ylmethyl)disulfanyl]pent-2-en-2-yl}formamide
• Retar B₁
• Tetrahydrofurfuryl thiamine disulfide
• Thiamin tetrahydrofurfuryl disulfide

Formamide,N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-

CAS: 804-30-8

Formula: C₁₇H₂₆N₄O₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.5433

Ref: IN-DA01CBCQ

Fursultiamine, 10mM (in DMSO)

CAS: 804-30-8

Fursultiamine, 10mM (in DMSO)

Purity: ≥98%

Molecular weight: 398.54g/mol

Ref: 54-BUP19966

Fursultiamine

CAS: 804-30-8

Fursultiamine

Purity: ≥98%

Molecular weight: 398.54g/mol

Ref: 54-BUP06909

Fursultiamine

CAS: 804-30-8

Formula: C₁₇H₂₆N₄O₃S₂

Purity: ≥ 98.0%

Color and Shape: White to off-white or pale yellow powder

Molecular weight: 398.54

Ref: 7W-GX9422

Fursultiamine

CAS: 804-30-8

Formula: C₁₇H₂₆N₄O₃S₂

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 398.54

Ref: 3B-F1364

Fursultiamine

CAS: 804-30-8

Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.

Formula: C₁₇H₂₆N₄O₃S₂

Purity: 99.63% - 99.90%

Color and Shape: Solid

Molecular weight: 398.54

Ref: TM-T4552

Fursultiamine

Controlled Product

CAS: 804-30-8

Applications Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases.
References Park, W., et al.: Clin. Ther., 38, 2277 (2016); Kosaka, T., et al.: Cancer Sci., 104, 1017 (2013); Lonsdale, D., et al.: Med. Sci. Monit., 10, 199 (2004)

Formula: C₁₇H₂₆N₄O₃S₂

Color and Shape: Neat

Molecular weight: 398.54

Ref: TR-F865235

Thiamine tetrahydrofurfuryl disulfide

CAS: 804-30-8

Thiamine tetrahydrofurfuryl disulfide is a thiamine derivative that has been shown to serve as a cofactor for enzymes such as peptidyl-prolyl cis-trans isomerase, which catalyzes the formation of peptide hormones. It also plays a role in the synthesis of polymers such as cellulose. Thiamine tetrahydrofurfuryl disulfide can be found in crystalline cellulose and is an important component of two-way crossover studies on peptide hormones. This drug has been shown to stimulate oxidative metabolism in cells and may have therapeutic potential for treating conditions associated with oxidative injury, such as stroke, head trauma, and heart attack.
Thiamine tetrahydrofurfuryl disulfide may also have a role in the development of inflammatory responses through its interaction with toll-like receptor 4 (TLR4).

Formula: C₁₇H₂₆N₄O₃S₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 398.55 g/mol

Ref: 3D-FT40945

FURSULTIAMINE

CAS: 804-30-8

Purity: 98%

Molecular weight: 398.5400085

Ref: 10-F806208