CAS 80434-86-2

(D-pro2

Description:

The chemical substance known as (D-pro2), with the CAS number 80434-86-2, is a synthetic compound that is primarily recognized for its role in biochemical research and applications. It is a derivative of proline, an amino acid that plays a crucial role in protein synthesis and structure. (D-pro2) is characterized by its specific stereochemistry, which influences its biological activity and interactions with various enzymes and receptors. This compound is often utilized in studies related to peptide synthesis, drug design, and the exploration of metabolic pathways. Its solubility, stability, and reactivity can vary depending on the conditions and the presence of other chemical species. As with many synthetic amino acid derivatives, (D-pro2) may exhibit unique properties that make it valuable in pharmaceutical development and biochemical assays. Safety and handling precautions should be observed, as with all chemical substances, to mitigate any potential hazards associated with its use.

Formula: C₇₄H₁₀₆N₂₀O₁₃S

InChI: InChI=1/C74H106N20O13S/c1-42(2)36-55(66(100)85-51(63(79)97)30-35-108-3)89-68(102)58(39-45-41-84-50-22-10-8-19-47(45)50)92-67(101)56(37-43-16-5-4-6-17-43)90-69(103)57(38-44-40-83-49-21-9-7-18-46(44)49)91-65(99)52(26-28-61(77)95)86-64(98)53(27-29-62(78)96)87-70(104)60-25-15-34-94(60)73(107)54(23-11-12-31-75)88-71(105)59-24-14-33-93(59)72(106)48(76)20-13-32-82-74(80)81/h4-10,16-19,21-22,40-42,48,51-60,83-84H,11-15,20,23-39,75-76H2,1-3H3,(H2,77,95)(H2,78,96)(H2,79,97)(H,85,100)(H,86,98)(H,87,104)(H,88,105)(H,89,102)(H,90,103)(H,91,99)(H,92,101)(H4,80,81,82)/t48-,51-,52?,53-,54-,55?,56-,57+,58+,59+,60-/m0/s1

Synonyms:

• (D-Pro2,D-Trp79)-Substance P
• H-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH2
• (D-pro2
• [D-PRO2,D-TRP7,9]-SUBSTANCE P HYDROCHLORIDE
• 2,D-Trp7,9>-SP
• (D-Pro2,D-Trp7
• 2-Pro-7,9-Trp-substance p
• dt79
• 2-Pro-7,9-Trp-sp
• L-Arg-D-Pro-L-Lys-L-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-L-Leu-L-Met-NH2
• Substance p, 2-D-proline-7-D-tryptophan-9-D-tryptophan-
• Pttsp
• Substance P, (D-Pro2, D-Trp7,9) acetate
• L-Arg-D-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-D-Trp-L-Phe-D-Trp-L-Leu-L-Met-NH2
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2 3HCL 6H2O
• Substance p, Pro(2)-Trp(7,9)-
• Pt-sp
• L-Methioninamide, L-arginyl-D-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2
• [D-PRO2,D-TRP7,9]-SUBSTANCE P 3HCL 6H2O
• substance P, prolyl(2)-tryptophan(7,9)-
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2 HYDROCHLORIDE

[D-Pro2,D-Trp7,9]-Substance P

CAS: 80434-86-2

This product is a Substance P antagonist and is available as a 0.5mg vial. Substance P is a neuropeptide that is involved in the transmission of pain signals and inflammation. It is a member of the tachykinin neuropeptide family and is produced in the central nervous system and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.

Formula: C₇₄H₁₀₆N₂₀O₁₃S

Purity: Min. 95%

Molecular weight: 1,515.8 g/mol

Ref: 3D-PSP-4113-V

(D-Pro2,D-Trp7·9)-Substance P acetate salt

CAS: 80434-86-2

Substance P is a neuropeptide that is involved in pain perception, the cardiovascular system, and cancer. It has been shown to affect blood pressure in rats by activating the sympathetic nervous system and increasing blood vessel tone. It also has anticancer activity and may be used as a potential therapeutic agent for the treatment of cancer. Research has shown that Substance P may be an important regulator of cancer cell proliferation and metastasis. In addition, this peptide is a potent analgesic, with effects on both fast-twitch muscle tissue and slow-twitch muscle tissue. The effect on slow-twitch muscle tissue is not blocked by antagonists of the neurokinin-1 receptor (NK1R), suggesting that it may not be mediated through NK1 receptors.

Formula: C₇₄H₁₀₆N₂₀O₁₃S

Purity: Min. 95%

Molecular weight: 1,515.83 g/mol

Ref: 3D-FP108553