CAS 8050-81-5

Simethicone

Description:

Simethicone, with the CAS number 8050-81-5, is a silicone-based compound primarily used as an anti-foaming agent. It is a mixture of polydimethylsiloxane and silica, which gives it unique properties that help reduce surface tension, thereby preventing the formation of gas bubbles in liquids. Simethicone is non-toxic, inert, and does not absorb into the body, making it safe for use in both pharmaceutical and food applications. It is commonly found in over-the-counter medications for relieving symptoms of gas, bloating, and discomfort associated with excessive gas in the digestive tract. Additionally, simethicone is utilized in various industrial applications, including cosmetics and personal care products, due to its ability to enhance texture and stability. Its effectiveness is attributed to its ability to coalesce small gas bubbles into larger ones, which can then be expelled more easily. Overall, simethicone is valued for its safety, efficacy, and versatility across multiple industries.

Formula: Unspecified

InChI: InChI=1/C6H18O2Si2.O2Si/c1-7-10(5,6)8-9(2,3)4;1-3-2/h1-6H3;

Synonyms:

• Aligest Plus
• Antifoam A
• Barcroft SIM-DC 100
• DC Antifoam A
• Dimethyl polysiloxane
• Dow Antifoam A
• Dow Corning Antifoam A
• Espumisan
• Gas-X
• KS 66 (silicone)
• Ks 66
• Mylicon
• Polymethylsiloxane, activated
• Q 7-2587
• Sentry Simethicone GS
• Silfoam SE 2
• Simiticone
• SonoRx
• Xiameter AFE 0100
• Xiameter AFE 0100 AF Emul FG
• Xiameter AFE 0100 Antifoam Emulsion Food Grade

Simethicone

CAS: 8050-81-5

Silicones in primary forms

Formula: (CH₃)₃SiOSi(CH₃)₂nCH₃SiO₂

Color and Shape: Translucent Grey Viscous Liquid

Molecular weight: 130.2603

Ref: 45-1612652

Simethicone

CAS: 8050-81-5

Formula: C₆H₁₈O₄Si₃

Purity: 90.5%

Color and Shape: Liquid

Molecular weight: 238.4612

Ref: IN-DA01CCI0

Simethicone

CAS: 8050-81-5

Simethicone

Purity: 90.5%-99%,800-1200 mpa.s

Ref: 54-OR1028729

Simethicone

CAS: 8050-81-5

Simethicone

Purity: ≥95%

Ref: 54-BUP19874

Simethicone

CAS: 8050-81-5

Formula: (C₂H₈O₂Si)n(SiO₂)m

Ref: 4Z-S-129001

Simethicone

CAS: 8050-81-5

Simethicone (Disflatyl), an oral anti-foaming agent, can be used to reduce bloating, pain and discomfort caused by excess gas in the stomach or intestinal tract

Formula: (C₂H₆OSi)n(SiO₂)m

Color and Shape: Solid

Ref: TM-T20914

Simethicone

CAS: 8050-81-5

Applications Simethicone is an oral anti-foaming agent used to reduce bloating, discomfort and pain caused by excess gas in the stomach or intestinal tract. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel.
References Grinshpan, D., et al.: Pharmaceut. Chem. J., 42, 400 (2008), Agarwal, D., et al.: J. Pharmac., 20, 206 (1988),

Formula: (C₂H₆OSi)n•SiO₂

Color and Shape: Clear Colourless

Molecular weight: 296.62

Ref: TR-S475600

Simethicone Deuterated

Controlled Product

CAS: 8050-81-5

Formula: (CD₃OSi)n•SiO₂

Color and Shape: Neat

Molecular weight: (62.14)n •60.08

Ref: TR-S475602

Simethicone-Viscosity 500cP

CAS: 8050-81-5

Simethicone-Viscosity 500cP is a research chemical that is used to estimate the concentration of pharmaceuticals in wastewater. It is used in the dilution and estimation of pharmaceuticals in wastewater, as well as monitoring their environmental risk. This chemical is not toxic to aquatic organisms such as daphnia, but it may be deficient in some environments due to its low solubility. Simethicone-Viscosity 500cP has been shown to have a low toxicity for humans, which may be due to its rapid metabolism by esterases. The medicinal uses of this substance are still being researched.

Color and Shape: Colorless Clear Liquid

Molecular weight: 238.46

Ref: 3D-FS31693