CAS 80522-42-5

Triisopropylsilyl trifluoromethanesulfonate

Description:

Triisopropylsilyl trifluoromethanesulfonate, with the CAS number 80522-42-5, is an organosilicon compound commonly used as a reagent in organic synthesis, particularly in the field of protecting groups for alcohols and amines. This compound features a trifluoromethanesulfonate group, which is a strong electrophile, making it effective for various chemical transformations. It is characterized by its relatively high stability under standard conditions, but it can be reactive towards nucleophiles. The presence of the triisopropylsilyl group enhances its solubility in organic solvents, facilitating its use in diverse synthetic applications. Additionally, the trifluoromethanesulfonate moiety contributes to its ability to act as a leaving group in nucleophilic substitution reactions. Safety precautions should be observed when handling this compound, as it can be hazardous due to its reactivity and potential toxicity. Overall, triisopropylsilyl trifluoromethanesulfonate is a valuable tool in synthetic organic chemistry, particularly for the protection and activation of functional groups.

Formula: C₁₀H₂₁F₃O₃SSi

InChI: InChI=1/C10H21F3O3SSi/c1-7(2)18(8(3)4,9(5)6)16-17(14,15)10(11,12)13/h7-9H,1-6H3

SMILES: CC(C)[Si](C(C)C)(C(C)C)OS(=O)(=O)C(F)(F)F

Synonyms:

• Triisopropylsilyltrifluoromethanesulfonate
• Tris(1-Methylethyl)Silyl Trifluoromethanesulfonate
• Trifluoromethanesulfonic Acid Triisopropylsilyl Ester
• Tips Triflate
• Silane Ip3-Triflate
• Tips-Otf
• (i-Pr)3SiOTf

Triisopropylsilyl Trifluoromethanesulfonate

CAS: 80522-42-5

Formula: C₁₀H₂₁F₃O₃SSi

Purity: >98.0%(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 306.42

Ref: 3B-T1588

Triisopropylsilyl trifluoromethanesulfonate, 97%

CAS: 80522-42-5

Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized espe

Formula: C₁₀H₂₁F₃O₃SSi

Purity: 97%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 306.42

Ref: 02-B21127

Triisopropylsilyl Trifluoromethanesulfonate

CAS: 80522-42-5

Formula: C₁₀H₂₁F₃O₃SSi

Purity: 95%

Color and Shape: Liquid

Molecular weight: 306.4176

Ref: IN-DA003V2X

Triisopropylsilyl trifluoromethanesulfonate

CAS: 80522-42-5

Triisopropylsilyl trifluoromethanesulfonate

Formula: C₁₀H₂₁F₃O₃SSi

Purity: 97%

Color and Shape: clear. colourless liquid

Molecular weight: 306.42g/mol

Ref: 54-PC58047

Triisopropylsilyl trifluoromethanesulphonate

CAS: 80522-42-5

S18050 - Triisopropylsilyl trifluoromethanesulphonate

Formula: C₁₀H₂₁F₃O₃SSi

Purity: 99%

Color and Shape: Clear

Molecular weight: 306.42

Ref: 10-S18050

Triisopropylsilyl Trifluoromethanesulfonate

Controlled Product

CAS: 80522-42-5

Formula: C₁₀H₂₁F₃O₃SSi

Color and Shape: Neat

Molecular weight: 306.42

Ref: TR-T790550

Triisopropylsilyl trifluoromethanesulphonate

CAS: 80522-42-5

Triisopropylsilyl trifluoromethanesulphonate (TIPS) is a naturally occurring compound that inhibits the enzyme dipeptidyl peptidase IV (DPP-IV). It has been shown to be active against alopecia areata in a mouse model and may have therapeutic potential for other autoimmune diseases. TIPS also has an inhibitory effect on sodium-dependent glucose transport, which may be useful in the treatment of hypertension. The reactive group of TIPS is hydroxyl, which can form a covalent bond with serine proteases and inhibit their activity. This reaction mechanism provides a new way to treat disorders such as metabolic diseases and infectious diseases. TIPS also has an inhibitory effect on ns3 protease, which is involved in the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses.

Formula: C₁₀H₂₁F₃O₃SSi

Purity: Min. 95%

Color and Shape: Colourless Clear Liquid

Molecular weight: 306.42 g/mol

Ref: 3D-FT31908