CAS 80529-93-7

Gd-DTPA

Description:

Gd-DTPA, or gadopentetate dimeglumine, is a paramagnetic contrast agent commonly used in magnetic resonance imaging (MRI). It consists of gadolinium, a rare earth metal, chelated with diethylenetriaminepentaacetic acid (DTPA), which enhances its stability and reduces toxicity. Gd-DTPA is characterized by its ability to shorten T1 relaxation times in tissues, thereby increasing the contrast of images obtained during MRI scans. This compound is water-soluble and typically administered intravenously, allowing for effective visualization of vascular structures and lesions. Its paramagnetic properties arise from the presence of gadolinium, which has unpaired electrons that influence the magnetic field. Gd-DTPA is generally well-tolerated, although it can pose risks in patients with renal impairment due to the potential for nephrogenic systemic fibrosis. The substance is also subject to strict regulatory guidelines to ensure patient safety during imaging procedures. Overall, Gd-DTPA plays a crucial role in enhancing diagnostic capabilities in medical imaging.

Formula: C₁₄H₁₈GdN₃O₁₀·2H

InChI: InChI=1S/C14H23N3O10.Gd/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);/q;+3/p-3

InChI key: InChIKey=IZOOGPBRAOKZFK-UHFFFAOYSA-K

SMILES: O=C1[O-][Gd+3]234567[N](CC(=O)[O-]2)(CC(=O)[O-]3)CC[N]4(C1)CC[N]5(CC(=O)[O-]6)CC(=O)[O-]7.[H+]

Synonyms:

• (Diethylenetriaminepentaacetato)gadolinium
• Acide gadopentetique
• Acide gadopentetique [French]
• Acido gadopentetico
• Acido gadopentetico [Spanish]
• Acidum gadopenteticum
• Acidum gadopenteticum [Latin]
• Gadolinate(2-), (N,N-bis(2-(bis((carboxy-kappaO)methyl)amino-kappaN)ethyl)glycinato(5-)-kappaN,kappaO)-, dihydrogen
• Gadolinate(2-), (N,N-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))-, dihydrogen
• Gadolinate(2-), [N,N-bis[2-[bis[(carboxy-κO)methyl]amino-κN]ethyl]glycinato(5-)-κN,κO]-, dihydrogen
• Gadolinate(2-), [N,N-bis[2-[bis[(carboxy-κO)methyl]amino-κN]ethyl]glycinato(5-)-κN,κO]-, hydrogen (1:2)
• Gadolinium Hydrogen 2,2',2'',2''',2''''-(Ethane-1,2-Diylnitrilo)Pentaacetate (1:2:1)
• Gadolinium diethylenetriamine pentaacetic acid
• Gadolinium dtpa
• Gadopentetic Acid [INN:BAN]
• Gd-DTPA
• Glycine, N,N-bis[2-[bis(carboxymethyl)amino]ethyl]-, gadolinium complex
• Unii-K2I13Dr72L
• gadolinium (bis{2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}amino)acetate - (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:1:2) (non-preferred name)

Gadopentetic acid

CAS: 80529-93-7

Gadopentetic acid

Purity: ≥95%

Molecular weight: 547.57g/mol

Ref: 54-BUP17307

Gadopentetic Acid

CAS: 80529-93-7

Formula: C₁₀H₁₂N₃O₁₀·Gd

Molecular weight: 334.22 157.25

Ref: 4Z-G-062001

Gadopentetic acid

CAS: 80529-93-7

Gadopentetic acid (Gd-DTPA), a gadolinium complex, is a paramagnetic MRI contrast agent used in bolus i.v. injections for DCE-MRI.

Formula: C₁₄H₂₀GdN₃O₁₀

Purity: 98%

Color and Shape: White Crystalline Powder

Molecular weight: 547.57

Ref: TM-T19332

Gadopentetic Acid

Controlled Product

CAS: 80529-93-7

Applications: Gadopentetic Acid is a magnetic resonance contrast agent being used to develop a new platform for the delivery of therapeutic and imaging agents simultaneously to the colon.
References Jin, M., et al.: Mol. Pharm, 13, 2457-2465 (2016)

Formula: C₁₄H₂₀GdN₃O₁₀

Color and Shape: Neat

Molecular weight: 547.57

Ref: TR-G125775