CAS 80651-94-1

N-succinyl-phe-leu-phe thiobenzyl ester

Description:

N-succinyl-phe-leu-phe thiobenzyl ester, identified by its CAS number 80651-94-1, is a synthetic peptide derivative characterized by its unique structure, which includes a succinyl group and a thiobenzyl ester moiety. This compound is typically used in biochemical research, particularly in studies related to peptide synthesis and enzyme inhibition. Its structure suggests that it may exhibit specific interactions with biological targets, potentially influencing enzymatic activity or receptor binding. The presence of the thiobenzyl group may enhance lipophilicity, affecting its solubility and permeability in biological systems. Additionally, the peptide sequence, comprising phenylalanine (Phe) and leucine (Leu), may contribute to its biological activity and stability. As with many peptide derivatives, its properties can be influenced by factors such as pH, temperature, and the presence of other ions or molecules in solution. Overall, N-succinyl-phe-leu-phe thiobenzyl ester serves as a valuable tool in the exploration of peptide chemistry and its applications in medicinal chemistry and drug design.

Formula: C₃₅H₄₁N₃O₆S

Synonyms:

• Suc-Phe-Leu-Phe-SBzl

Suc-Phe-Leu-Phe-SBzl

CAS: 80651-94-1

Suc-FLF-thiobenzyl ester, a very sensitive substrate for the determination of cathepsin G activity. It is also cleaved by chymotrypsin, chymotrypsin-like serine proteases from skin as well as rat mast cell proteases.

Formula: C₃₅H₄₁N₃O₆S

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 631.79

Ref: 01-4006633

Suc-Phe-Leu-Phe-SBzl

CAS: 80651-94-1

Suc-Phe-Leu-Phe-SBzl is a protease inhibitor that blocks the activity of serine proteases and inhibits protein synthesis. It has been shown to be active against a number of proteases, such as trypsin, chymotrypsin, elastase, and cathepsin G. Suc-Phe-Leu-Phe-SBzl has been reported to inhibit the activity of serine proteases at low concentrations but not at high concentrations. This drug also has a potent effect on cellular organelles such as mitochondria and lysosomes. The enzyme inhibition property of Suc-Phe-Leu-Phe-SBzl is due to its ability to bind strongly to proteins with hydrophobic amino acid residues in their active site.

Formula: C₃₅H₄₁N₃O₆S

Purity: Min. 95%

Molecular weight: 631.78 g/mol

Ref: 3D-FS110880