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CAS 80663-95-2

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meta-Iodobenzylguanidine

Description:
Meta-Iodobenzylguanidine (MIBG) is a chemical compound that belongs to the class of guanidine derivatives. It is characterized by the presence of an iodine atom at the meta position of the benzyl ring, which enhances its biological activity. MIBG is primarily known for its application in medical imaging and treatment, particularly in the diagnosis and therapy of neuroendocrine tumors, such as pheochromocytoma and neuroblastoma. The compound exhibits a high affinity for norepinephrine transporters, allowing it to selectively accumulate in adrenergic tissues. MIBG is typically administered in a radiolabeled form for scintigraphy, enabling visualization of tumors through imaging techniques. In terms of physical properties, MIBG is a solid at room temperature and is soluble in organic solvents. Its stability and reactivity are influenced by the presence of the iodine atom, which can participate in various chemical reactions. Overall, MIBG serves as a valuable tool in both diagnostic and therapeutic applications in the field of nuclear medicine.
Formula:C8H10IN3
InChI:InChI=1S/C8H10IN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)
InChI key:InChIKey=PDWUPXJEEYOOTR-UHFFFAOYSA-N
SMILES:C(NC(=N)N)C1=CC(I)=CC=C1
Synonyms:
  • (3-Iodobenzyl)guanidine
  • 1-(3-Iodobenzyl)Guanidine Sulfate (2:1)
  • Guanidine, ((3-iodophenyl)methyl)-
  • Guanidine, N-[(3-iodophenyl)methyl]-
  • Iobenguane
  • N-[(3-Iodophenyl)methyl]guanidine
  • Unii-35Mrw7B4Ad
  • m-Iodobenzylguanidine
  • meta-Iodobenzylguanidine
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